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. 2024 Jul 10;32(7):1039-1041.
doi: 10.1016/j.chom.2024.06.009.

Chaperones help TACkle phage infection

Shally R Margolis  1 , Alexander J Meeske  2
Affiliations
Free article

Chaperones help TACkle phage infection

Shally R Margolis et al. Cell Host Microbe. .
Free article

Abstract

Bacteria have evolved anti-viral defenses, but the mechanisms of sensing and stopping infection are still under investigation. In this issue of Cell Host & Microbe, Mets, Kurata, Ernits et al. describe how direct sensing of a phage protein by a bacterial toxin-antitoxin-associated chaperone unleashes toxin activity to prevent infection.

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Conflict of interest statement

Declaration of interests A.J.M. is a co-founder of Profluent Bio.

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