Review
doi: 10.1016/s0300-9084(85)80079-1.
Role of Escherichia coli RecA protein in SOS induction and post-replication repair
- PMID: 3899189
- DOI: 10.1016/s0300-9084(85)80079-1
Item in Clipboard
Review
Role of Escherichia coli RecA protein in SOS induction and post-replication repair
Biochimie.
1985 Mar-Apr.
Abstract
The RecA protein of Escherichia coli plays a central role in DNA repair mechanisms. When it is incubated with single-stranded DNA and a nucleoside triphosphate, the purified RecA protein acts both by promoting cleavage of the LexA protein, the repressor of the SOS genes, and by catalyzing strand exchange between a variety of DNA molecules. A model for the regulation of the activity of the RecA protein in a cell exposed to a DNA damaging treatment is proposed.
Similar articles
-
P. mirabilis RecA protein catalyses cleavage of E. coli LexA protein and the lambda repressor in vitro.Mol Gen Genet. 1984;194(1-2):111-3. doi: 10.1007/BF00383505. Mol Gen Genet. 1984. PMID: 6374373
-
Purification and characterization of the RecA protein from Streptococcus pneumoniae.Arch Biochem Biophys. 2000 Oct 15;382(2):303-9. doi: 10.1006/abbi.2000.2029. Arch Biochem Biophys. 2000. PMID: 11068882
-
Effects of overproduction of single-stranded DNA-binding protein on RecA protein-dependent processes in Escherichia coli.J Mol Biol. 1987 Apr 20;194(4):621-34. doi: 10.1016/0022-2836(87)90239-7. J Mol Biol. 1987. PMID: 3309327
-
The SOS regulatory system of Escherichia coli.Cell. 1982 May;29(1):11-22. doi: 10.1016/0092-8674(82)90085-x. Cell. 1982. PMID: 7049397 Review. No abstract available.
-
[Bacterial RecA protein: a biochemical, genetic and physicochemical analysis].Genetika. 1985 Sep;21(9):1413-27. Genetika. 1985. PMID: 3905509 Review. Russian.
Cited by
-
Identification of a DNA-damage-inducible regulon in Acinetobacter baumannii.J Bacteriol. 2013 Dec;195(24):5577-82. doi: 10.1128/JB.00853-13. Epub 2013 Oct 11. J Bacteriol. 2013. PMID: 24123815 Free PMC article.
-
Translesion DNA polymerases are required for spontaneous deletion formation in Salmonella typhimurium.Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10248-53. doi: 10.1073/pnas.0904389106. Epub 2009 Jun 12. Proc Natl Acad Sci U S A. 2009. PMID: 19525399 Free PMC article.
-
Regulation of Cell Division in Bacteria by Monitoring Genome Integrity and DNA Replication Status.J Bacteriol. 2020 Jan 2;202(2):e00408-19. doi: 10.1128/JB.00408-19. Print 2020 Jan 2. J Bacteriol. 2020. PMID: 31548275 Free PMC article. Review.
-
Effect of translesion DNA polymerases, endonucleases and RpoS on mutation rates in Salmonella typhimurium.Genetics. 2010 Jul;185(3):783-95. doi: 10.1534/genetics.110.116376. Epub 2010 Apr 26. Genetics. 2010. PMID: 20421601 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
