Review
doi: 10.1016/s0300-9084(85)80086-9.
Chemical carcinogens and proto-oncogens activation
- PMID: 3899192
- DOI: 10.1016/s0300-9084(85)80086-9
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Review
Chemical carcinogens and proto-oncogens activation
Biochimie.
1985 Mar-Apr.
Abstract
The induction of proto-oncogens H-ras-1 by nitrosomethylurea (Sukumar et al. (1983), 306, 658-661) is discussed in term of lack of DNA-repair of lesions induced in DNA by this alkylating agent, particularly O6-methylguanine residues and apurinic/apyrimidinic sites.
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