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. 2024 Aug;15(4):675-681.
doi: 10.14740/wjon1875. Epub 2024 Jul 5.

Use of Period Analysis to Timely Assess Five-Year Relative Survival for the Patients With Bone Cancer

Xian Kuan Xie  1   2 , Xiao Jiao Zhao  3   4   2 , Run Hua Li  4   5 , Yong Ran Cheng  6 , Xin Bing  3   4 , Jun Yang  3 , Liang You Wang  7 , Hui Jun Zhu  8 , Tian Hui Chen  4   5 , Jin Fei Chen  9
Affiliations

Use of Period Analysis to Timely Assess Five-Year Relative Survival for the Patients With Bone Cancer

Xian Kuan Xie et al. World J Oncol. 2024 Aug.

Abstract

Background: While timely assessment of long-term survival for patients with bone cancer is essential for evaluation on early detection and prognosis level of treatment of bone cancer, those data are extremely scarce in China. We aimed to timely and accurately assess long-term survival for patients with bone cancer in Eastern China.

Methods: Patients diagnosed with bone cancer during 2004 - 2018 from four cancer registries with high-quality data from Taizhou, Eastern China were included. Five-year relative survival (RS) of bone cancer patients was calculated by period analysis for overall and the stratification. We further predicted 5-year RS during upcoming 2019 - 2023 using a model-based period analysis and survival data during 2004 - 2018.

Results: Overall, 5-year RS for patients with bone cancer during 2014 - 2018 reached 46.6%, being 40.8% for male and 51.0% for female. Five-year RS declined along with aging, decreasing from 58.9% for age < 45 years to 41.5% for age > 60 years, while 5-year RS for urban area was higher compared to rural area (59.1% vs. 44.3%). The 5-year RS during upcoming 2019 - 2023 reached 48.3%. We found a clear upward trend in 5-year RS during 2004 - 2023 for overall and the stratification by sex, age at diagnosis, and region.

Conclusions: We found that, for first time in China using period analysis, most up-to-date 5-year RS for patients with bone cancer reached 46.6% during 2014 - 2018, and is projected to reach 48.3% for the period 2019 - 2023, which has important implications for timely evaluation on early detection and prognosis level of treatment for patients with bone cancer in Eastern China.

Keywords: Bone cancer; Cancer registry; Five-year relative survival; Period analysis.

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Conflict of interest statement

None to declare.

Figures

Figure 1
Figure 1
Five-year relative survival for overall and the stratification by sex for patients with bone cancer from Taizhou, Eastern China during 2004 - 2008, 2009 - 2013, 2014 - 2018 and 2019 - 2023.
Figure 2
Figure 2
Five-year relative survival for overall and the stratification by age at diagnosis for patients with bone cancer from Taizhou, Eastern China during 2004 - 2008, 2009 - 2013, 2014 - 2018 and 2019 - 2023.
Figure 3
Figure 3
Five-year relative survival for overall and the stratification by region (urban and rural areas) for patients with bone cancer from Taizhou, Eastern China during 2004 - 2008, 2009 - 2013, 2014 - 2018 and 2019 - 2023.
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