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Review
. 2024 Jun 27:11:1333005.
doi: 10.3389/fcvm.2024.1333005. eCollection 2024.

Gut microbiota: a potential new regulator of hypertension

Yanmin Ge  1 , Jiaxin Wang  2 , Lincong Wu  1 , Junduo Wu  1
Affiliations
Review

Gut microbiota: a potential new regulator of hypertension

Yanmin Ge et al. Front Cardiovasc Med. .

Abstract

Hypertension is a significant risk factor for cardiovascular and cerebrovascular diseases and has become a global public health concern. Although hypertension results from a combination of factors, the specific mechanism is still unclear. However, increasing evidence suggests that gut microbiota is closely associated with the development of hypertension. We provide a summary of the composition and physiological role of gut microbiota. We then delve into the mechanism of gut microbiota and its metabolites involved in the occurrence and development of hypertension. Finally, we review various regimens for better-controlling hypertension from the diet, exercise, drugs, antibiotics, probiotics, and fecal transplantation perspectives.

Keywords: blood pressure; gut microbiota; hypertension; lipopolysaccharide; short-chain fatty acids.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
The role of gut microbiota in hypertension.
Figure 2
Figure 2
Selection of treatment plans for gut microbiota in patients with hypertension.
See this image and copyright information in PMC

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