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Review
. 2024 Jul 12;22(1):63.
doi: 10.1186/s12959-024-00636-1.

Combination of graduated compression stockings and intermittent pneumatic compression is better in preventing deep venous thrombosis than graduated compression stockings alone for patients following gynecological surgery: a meta-analysis

Limei Lu #  1 , Ya Shen #  2 , Yuping Pan  3
Affiliations
Review

Combination of graduated compression stockings and intermittent pneumatic compression is better in preventing deep venous thrombosis than graduated compression stockings alone for patients following gynecological surgery: a meta-analysis

Limei Lu et al. Thromb J. .

Abstract

Background: Deep vein thrombosis (DVT) is common in patients undergoing gynecological surgery. We aimed to investigate the preventive efficacy in DVT of graduated compression stockings (GCS) alone and in combination with intermittent pneumatic compression (GCS + IPC) after gynecological surgery.

Methods: In November 2022, studies on the use of GCS and GCS + IPC for the prevention of DVT after gynecological surgery were searched in seven databases. After literature screening and data extraction based on specific inclusion and exclusion criteria, preventive efficacies, including the risk of DVT and anticoagulation function, of GCS and GCS + IPC were compared. Finally, sensitivity analysis and Egger's test were performed to evaluate the stability of the meta-analysis.

Results: Six publications with moderate quality were included in this meta-analysis. The results showed that GCS + IPC significantly reduced DVT risk (P = 0.0002) and D-dimer levels (P = 0.0005) compared with GCS alone. Sensitivity analysis and Egger's test showed that the combined results of this study were stable and reliable.

Conclusions: Compared with GCS alone, GCS + IPS showed a higher preventive efficacy against DVT in patients following gynecological surgery.

Keywords: Compression stockings; Deep venous thrombosis; Intermittent pneumatic compression device.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Process and results of the publication screening. CNKI, China National Knowledge Infrastructure; CQVIP, China Science and Technology Journal Database; GCS, graduated compression stockings; IPC, intermittent pneumatic compression
Fig. 2
Fig. 2
Forest plot of differences in the risk of DVT between the GCS + IPC and GCS groups. DVT, deep venous thrombosis
Fig. 3
Fig. 3
Forest plots of differences in coagulation function between GCS + IPC and GCS groups. PT, prothrombin time; APTT, activated partial thromboplastin time; TT, thrombin time; FIB, fibrinogen; PLT, platelet count
Fig. 4
Fig. 4
Funnel plot showing the distribution of the studies
See this image and copyright information in PMC

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