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Editorial
. 2024 Jul 14;10(3):e004481.
doi: 10.1136/rmdopen-2024-004481.

Course of paediatric ANCA-associated glomerulonephritis: advocating for an age-inclusive approach

Cecilia Barnini  1 , Louise Oni  2 , Andreas Kronbichler  3
Affiliations
Editorial

Course of paediatric ANCA-associated glomerulonephritis: advocating for an age-inclusive approach

Cecilia Barnini et al. RMD Open. .
No abstract available

Keywords: Child; Granulomatosis with polyangiitis; Vasculitis.

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Conflict of interest statement

Competing interests: LO received consulting fees from Biocryst Pharmaceuticals, Boehringer Ingelheim, Hansa Biopharmaceuticals, Hansa Biopharma and Sandoz. AK received consulting fees from Amgen, AstraZeneca, Boehringer Ingelheim, CSL Vifor, Delta4, GlaxoSmithKline, Novartis, Otsuka, Roche and Walden Biosciences, all outside the submitted work.

Figures

Figure 1
Figure 1. ANCA-associated glomerulonephritis is rare in children. Differences reported in this study and others include a skewed distribution towards more frequent AAV in females in comparison to males. Kidney disease is encountered more frequently in children with PR3-ANCA vasculitis in comparison to adults. More children present with a crescentic class according to the Berden histopathological classification, which is also associated with a greater kidney function recovery potential. In the short-term follow-up, the risk of relapse seems to be balanced in children with PR3-ANCA+ and MPO-ANCA+, which is in contrast to adults, where a higher relapse rate is reported in patients with PR3-ANCA+. This figure was created with the help of BioRender.com. ANCA, antineutrophil cytoplasmic antibody; eGFR, estimated glomerular filtration rate; MPO, myeloperoxidase; PR3, proteinase 3.
See this image and copyright information in PMC

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References

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