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. 2024 Jun 15;16(6):2435-2444.
doi: 10.62347/DHAJ4799. eCollection 2024.

Risk factors for benign paroxysmal positional vertigo and construction of a nomogram predictive model

Wenping Cao  1 , Yang Geng  1 , Jun Chang  2 , Feifei Li  1
Affiliations

Risk factors for benign paroxysmal positional vertigo and construction of a nomogram predictive model

Wenping Cao et al. Am J Transl Res. .

Abstract

Background: To analyze the risk factors for benign paroxysmal positional vertigo (BPPV) and to construct a predictive nomogram model.

Methods: In this retrospective study, 312 participants were enrolled, including 164 BPPV patients and 148 healthy subjects without BPPV. Risk predictors for BPPV were identified using univariate and multivariate analyses, and a clinical nomogram was constructed. The predictive accuracy was assessed by unadjusted concordance index (C-index) and calibration plot.

Results: Univariate and multivariate regression analysis identified stroke (95% CI, 0.575-5.954; P=0.022), hyperlipidemia (95% CI, 0.471-4.647; P=0.003), chronic suppurative otitis media (95% CI, 1.222-45.528; P=0.005), cervical spondylosis (95% CI, 1.232-3.017; P=0.005), and osteoporosis (95% CI, 1.130-3.071; P=0.001) were the independent risk factors for BPPV. These risk factors were used to construct a clinical predictive nomogram. The regression equation was: logit (P) = -6.820 + 0.450 * stroke + hyperlipidemia * 0.312 + chronic suppurative otitis media * 0.499 + cervical spondylosis * 0.916 + osteoporosis * 0.628. The calibration curves demonstrated excellent accuracy of the predictive nomogram. Decision curve analysis showed that the predictive model is clinically applicable when the threshold probability was between 20% and 60%.

Conclusions: Stroke, hyperlipidemia, chronic suppurative otitis media, cervical spondylosis and osteoporosis are independent risk predictors for BPPV. The developed nomogram is useful in predicting the risk of BPPV.

Keywords: Benign paroxysmal positional vertigo; nomogram; predictive effect; risk factors.

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Conflict of interest statement

None.

Figures

Figure 1
Figure 1
Nomogram for predicting the risk of BPPV. CSOM: chronic suppurative otitis media; CS: cervical spondylosis.
Figure 2
Figure 2
Calibration curves for nomogram in predicting BPPV risk. BPPV: Benign paroxysmal positional vertigo.
Figure 3
Figure 3
ROC curves of the monogram in predicting the BPPV risk. BPPV: Benign paroxysmal positional vertigo.
Figure 4
Figure 4
Decision curve analysis for the nomogram. BPPV: Benign paroxysmal positional vertigo.
See this image and copyright information in PMC

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