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. 2024 Jul 15;9(1):e001664.
doi: 10.1136/bmjophth-2024-001664.

Novel anthropometric indices are superior adiposity indexes to portend visual impairment in middle-aged and older Chinese population

Yifan Zhou #  1 , Qing Chen #  2 , KaiweiSa Abuduxukuer #  3   4   5 , Chuchu Wang #  3   4   5 , Jialong Dong  1 , Yiting Wang  6 , Wenming Shi  7 , Yanan Hou  8 , Fei Shi  9 , Jianfeng Luo  3   4   5 , Qing Peng  10
Affiliations

Novel anthropometric indices are superior adiposity indexes to portend visual impairment in middle-aged and older Chinese population

Yifan Zhou et al. BMJ Open Ophthalmol. .

Abstract

Objective: To investigate differential associations of traditional and novel adiposity indices with visual impairment (VI) in the middle-aged and older Chinese population.

Methods and analysis: Based on the China Health and Retirement Longitudinal Study, 7750 Chinese older adults aged over 45 were included at baseline 2011, and 4133 participants who accomplished all three interviews from 2011 to 2015 were adapted for longitudinal analyses. We enrolled six adiposity indices, including the body mass index (BMI), waist-to-height ratio (WHtR), weight-adjusted-waist index (WWI), a body shape index (ABSI), body roundness index (BRI) and conicity index (ConI). Visual status and other covariates included sociodemographic characteristics, medical supports and lifestyle-related factors. Cross-sectional correlations were assessed using univariate and multivariate logistic regression analyses. For longitudinal analysis, generalised linear models with generalised estimating equations were used to determine the association between time-varying adiposity and visual status.

Results: Higher levels of WHtR/WWI/ABSI/BRI/ConI were significantly associated with an increased prevalence of VI, whereas a higher BMI was associated with a decreased prevalence of VI. Only WWI was significantly related to the prevalence of VI after adjustment for multiple confounders in both cross-sectional and longitudinal analyses (all p values <0.05). The multivariable-adjusted OR (95% CI) of VI associated with the highest (vs lowest) quintile of WWI was 1.900 (1.407 to 2.565).

Conclusion: WWI is a reliable alternative adiposity index that exhibits a dose-response association with the prevalence of VI in the Chinese population. The WWI-VI correlation may eliminate the obesity paradox in the ophthalmic epidemiological area and indicate the detrimental impact of changes in body composition on VI.

Keywords: Epidemiology; Public health.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1. Sample screening of the present study. CHARLS, China Health and Retirement Longitudinal Study.
See this image and copyright information in PMC

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References

    1. Zhou Y, Wei J, Sun Q, et al. Do sensory impairments portend cognitive decline in older Chinese adults? Longitudinal evidence from a nationally representative survey, 2011-2018. J Clin Med. 2023;12:430. doi: 10.3390/jcm12020430. - DOI - PMC - PubMed
    1. Ehrlich JR, Ramke J, Macleod D, et al. Association between vision impairment and mortality: a systematic review and meta-analysis. Lancet Global Health. 2021;9:e418–30. doi: 10.1016/S2214-109X(20)30549-0. - DOI - PMC - PubMed
    1. Ng Yin Ling C, Seshasai S, Chee ML, et al. Visual impairment, major eye diseases, and mortality in a multi-ethnic Asian population and a meta-analysis of prospective studies. Am J Ophthalmol. 2021;231:88–100. doi: 10.1016/j.ajo.2021.04.026. - DOI - PubMed
    1. Thompson AC, Miller ME, Webb CC, et al. Relationship of self-reported and performance-based visual function with performance-based measures of physical function: the health ABC study. J Gerontol A Biol Sci Med Sci. 2023;78:2060–9. doi: 10.1093/gerona/glac225. - DOI - PMC - PubMed
    1. Zhou Y, Hu Y, Luo J, et al. Association between sensory loss and falls among middle-aged and older Chinese population: cross-sectional and longitudinal analyses. Front Med. 2021;8:810159. doi: 10.3389/fmed.2021.810159. - DOI - PMC - PubMed

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