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. 2024 Jul;40(3):549-550.
doi: 10.1007/s12288-024-01733-x. Epub 2024 Feb 4.

Acute Myeloid Leukemia t (8;21) with Masked Systemic Mastocytosis

M B Deepak  1 , S Bharath Ram  2   3 , Sudarshan Chougule  1 , Hema Subramanian  1 , K S Shalini  1 , Sharat Damodar  2
Affiliations

Acute Myeloid Leukemia t (8;21) with Masked Systemic Mastocytosis

M B Deepak et al. Indian J Hematol Blood Transfus. 2024 Jul.
No abstract available

Keywords: Acute myeloid leukemia; Masked; Mastocytosis; Systemic mastrocytosis with associated hematologic neoplasm (SM-AHN).

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Figures

Fig. 1
Fig. 1
(Left) Bone marrow aspiration at diagnosis, Wright Giemsa stain, 100×—Increase in blasts with Auer rod (displayed by arrow). (Right)Bone marrow aspiration after 3 cycles, Wright Giemsa stain, 100×—Spindled atypical mast cells in aggregates (displayed by arrows)
Fig. 2
Fig. 2
Flow cytometry dot plot data (3-laser and 8-colour BD FACS CANTO II instrument)—Atypical mast cells (purple color) with medium side scatter express CD117 with aberrant CD2 and CD25. Internal control includes lymphocytes (blue color) and myeloids (green color)
See this image and copyright information in PMC

References

    1. Arber DA, Orazi A, Hasserjian R, et al. The 2016 revision to the world health organization classification of myeloid neoplasms and acute leukemia. Blood. 2016;127(20):2391–2405. doi: 10.1182/blood-2016-03-643544. - DOI - PubMed
    1. Pullarkat ST, Pullarkat V, Kroft SH, et al. Systemic mastocytosis associated with t(8;21)(q22;q22) acute myeloid leukemia. J Hematop. 2009;2(1):27–33. doi: 10.1007/s12308-009-0023-2. - DOI - PMC - PubMed

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