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Meta-Analysis
. 2024 Jul 17;24(1):609.
doi: 10.1186/s12877-024-05155-2.

Use of the Ishii Test for screening sarcopenia in older adults: a systematic review with meta-analysis of diagnostic test accuracy (DTA) studies

Sabrina Gabrielle Gomes Fernandes Macêdo  1 , Pedro Rafael de Souza Macêdo  2 , Weslley Sales Barbosa  2 , Álvaro Campos Cavalcanti Maciel  2
Affiliations
Meta-Analysis

Use of the Ishii Test for screening sarcopenia in older adults: a systematic review with meta-analysis of diagnostic test accuracy (DTA) studies

Sabrina Gabrielle Gomes Fernandes Macêdo et al. BMC Geriatr. .

Abstract

Background: The Ishii Test is recommended by the European Working Group on Sarcopenia in Older People (EWGSOP2), however the use of this technique is still little explored in the clinical context and the scientific literature.

Objective: We aimed to verify the use of the Test of Ishii in screening for sarcopenia in older adults.

Methods: We searched three electronic databases and two reviewers independently screened and assessed the studies. Studies with older adults (60 years or more) of both genders, no year or language restriction and which aimed to evaluate sarcopenia using the Ishii Test and another diagnostic criteria were selected. A summary of the ROC curve, sensitivity and specificity were performed using the MedCalc and SPSS software programs, respectively.

Results: A total of 3,298 references were identified in the database, 278 by manually searching, and finally 11 studies were included for the review. The screening test showed good sensitivity and specificity in both genders. All studies showed values above the considered value for the Area Under the Curve (AUC) results, without discriminating power (0.500). Four studies used the original values, and five studies developed a new cut-off point. A summary of the AUC curve showed the diamond close to one, indicating that the Ishii test has good performance for screening sarcopenia (I2=83,66%; p<0.001; 95%CI: 69.38 to 91.28 for men; and I2=60.04%; p<0.001; 95%CI: 13.06 to 81.63 for women).

Conclusion: The Ishii Test can be considered a useful tool for the early identification of sarcopenia in older adults. However, further studies are still needed to understand the behavior of this screening tool.

Trial registration: CRD42023424392.

Keywords: Epidemiology; Geriatrics; Ishii test; Sarcopenia; Screening.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Flowchart of studies found for this review
Fig. 2
Fig. 2
A Summary of the ROC curves for men; B Summary of the ROC curves for women
Fig. 3
Fig. 3
Proportion of studies with low, high, or unclear risks of bias
See this image and copyright information in PMC

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