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Case Reports
. 2024 Jul 12;15(1):548-551.
doi: 10.1159/000539900. eCollection 2024 Jan-Dec.

Fluorescein Angiogram Causing Cutaneous Venous Staining: A Rare Self-Resolving Phenomenon

Zachary George Angus  1   2 , Daini Ong  1 , Sanjeewa S Wickremasinghe  1
Affiliations
Case Reports

Fluorescein Angiogram Causing Cutaneous Venous Staining: A Rare Self-Resolving Phenomenon

Zachary George Angus et al. Case Rep Ophthalmol. .

Abstract

Introduction: Fluorescein angiography (FA) is a useful investigation in the diagnosis and treatment of retinal and choroidal disease. FA has well-reported adverse effects, most being mild. Very few cases have reported cutaneous venous staining following FA.

Case presentation: Two cases are reported. Case 1 was a 90-year-old female with bilateral neovascular age-related macular degeneration. In the few minutes following her routine FA, she developed cutaneous fluorescein staining ascending along the superficial forearm veins proximal to the cannula in situ at the dorsal wrist. Case 2 was a 50-year-old male with diabetic macular oedema. In the minutes following his FA, he developed cutaneous fluorescein staining descending along the dorsal forearm veins distal to the cannula in situ at the cubital fossa. Both patients were managed conservatively with the stain resolving in the next few days.

Conclusion: Cutaneous fluorescein staining around superficial vasculature is a rare phenomenon. Despite this, it seems to be self-limiting and does not require any treatment.

Keywords: Adverse effect; Fluorescein angiography; Retina; Skin; Staining.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Fig. 1.
Fig. 1.
Cutaneous fluorescein staining ascending along the superficial forearm veins proximal to the cannula in situ at the dorsal wrist. Wide view (a) and close-up view (b).
Fig. 2.
Fig. 2.
Image of cutaneous fluorescein staining descending along the dorsal forearm veins distal to the cannula in situ at the cubital fossa (tape from cannula to left of image).
See this image and copyright information in PMC

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