Review
[New morphological aspects of pathogenesis of pneumofibrosis in anthracosis]
[Article in
Russian]
- PMID: 3901975
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Review
[New morphological aspects of pathogenesis of pneumofibrosis in anthracosis]
[Article in
Russian]
Arkh Patol.
1985.
Abstract
The death of the alveolar macrophage stimulating the activation of fibroblast in pneumoconiosis is not a single trigger mechanism of pneumofibrosis in anthracosis. Alteration of the microcirculatory bed and lung aerohematic barrier plays an essential pathogenetic role in coal pneumoconiosis. Polycarbonic acids which are formed in the organism from coal as a result of its oxidative-hydrolytic degradation are the cause of the damage and loss of the structural components of the aerohematic barrier.
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