Chemical herding as a multiplicative factor for top-down manipulation of colloids

Abstract

Colloidal particles can create reconfigurable nanomaterials, with applications such as color-changing, self-repairing, and self-regulating materials and reconfigurable drug delivery systems. However, top-down methods for manipulating colloids are limited in the scale they can control. We consider here a new method for using chemical reactions to multiply the effects of existing top-down colloidal manipulation methods to arrange large numbers of colloids with single-particle precision, which we refer to as chemical herding. Using simulation-based methods, we show that if a set of chemically active colloids (herders) can be steered using external forces (i.e., electrophoretic, dielectrophoretic, magnetic, or optical forces), then a larger set of colloids (followers) that move in response to the chemical gradients produced by the herders can be steered using the control algorithms given in this paper. We also derive bounds that predict the maximum number of particles that can be steered in this way, and we illustrate the effectiveness of this approach using Brownian dynamics simulations. Based on the theoretical results and simulations, we conclude that chemical herding is a viable method for multiplying the effects of existing colloidal manipulation methods to create useful structures and materials.