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. 2024 Oct;84(14):1271-1289.
doi: 10.1002/pros.24768. Epub 2024 Jul 17.

The 30th Annual Prostate Cancer Foundation Scientific Retreat Report

Andrea K Miyahira  1 , Howard R Soule  1
Affiliations

The 30th Annual Prostate Cancer Foundation Scientific Retreat Report

Andrea K Miyahira et al. Prostate. 2024 Oct.

Abstract

Background: The 30th Annual Prostate Cancer Foundation (PCF) Scientific Retreat was held at the Omni La Costa Resort in Carlsbad, CA, from October 26 to 28, 2023. A hybrid component was included for virtual attendees.

Methods: The Annual PCF Scientific Retreat is a leading international scientific conference focused on pioneering, unpublished, and impactful studies across the spectrum of basic through clinical prostate cancer research, as well as research from related fields with significant potential for improving prostate cancer research and patient outcomes.

Results: The 2023 PCF Retreat concentrated on key areas of research, including: (i) the biology of cancer stem cells and prostate cancer lineage plasticity; (ii) mechanisms of treatment resistance; (iii) emerging AI applications in diagnostic medicine; (iv) analytical and computational biology approaches in cancer research; (v) the role of nerves in prostate cancer; (vi) the biology of prostate cancer bone metastases; (vii) the contribution of ancestry and genomics to prostate cancer disparities; (viii) prostate cancer 3D genomics; (ix) progress in new targets and treatments for prostate cancer; (x) the biology and translational applications of tumor extracellular vesicles; (xi) updates from PCF TACTICAL Award teams; (xii) novel platforms for small molecule molecular glues and binding inhibitors; and (xiii) diversity, equity and inclusion strategies for advancing cancer care equity.

Conclusions: This meeting report summarizes the presentations and discussions from the 2023 PCF Scientific Retreat. We hope that sharing this information will deepen our understanding of current and emerging research and drive future advancements in prostate cancer patient care.

Keywords: androgen receptor; diagnosis; prognosis; therapy; tumor biology.

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References

REFERENCES

    1. Moad M, Hannezo E, Buczacki SJ, et al. Multipotent basal stem cells, maintained in localized proximal niches, support directed long‐ranging epithelial flows in human prostates. Cell Rep. 2017;20(7):1609‐1622.
    1. Blackwood JK, Williamson SC, Greaves LC, et al. In situ lineage tracking of human prostatic epithelial stem cell fate reveals a common clonal origin for basal and luminal cells. J Pathol. 2011;225(2):181‐188.
    1. Grossmann S, Hooks Y, Wilson L, et al. Development, maturation, and maintenance of human prostate inferred from somatic mutations. Cell Stem Cell. 2021;28(7):1262‐1274.e5.
    1. Chan JM, Zaidi S, Love JR, et al. Lineage plasticity in prostate cancer depends on JAK/STAT inflammatory signaling. Science. 2022;377(6611):1180‐1191.
    1. Moad M, Pal D, Hepburn AC, et al. A novel model of urinary tract differentiation, tissue regeneration, and disease: reprogramming human prostate and bladder cells into induced pluripotent stem cells. Eur Urol. 2013;64(5):753‐761.

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