Effects of opioid-based versus opioid-free anaesthesia on blinded nociception level index values during laparoscopic gastric bypass surgery: a secondary analysis of a randomised double-blind trial

Affiliations

¹ Department of Anaesthesiology and Intensive Care, Paris-Saclay University, Paul Brousse Hospital, Assistance Publique Hôpitaux de Paris, Villejuif, France.
² Outcomes Research Consortium, Cleveland, OH, USA.
³ Cell Death and Inflammation Unit, VIB-UGent Center for Inflammation Research (IRC), Ghent, Belgium.
⁴ Department of Anaesthesiology, Chirec Delta Hospital, Brussels, Belgium.
⁵ Department of General Surgery, Chirec Delta Hospital, Brussels, Belgium.
⁶ Department of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.

Sean Coeckelenbergh et al. BJA Open. 2024.

. 2024 Jun 20:11:100295.

doi: 10.1016/j.bjao.2024.100295. eCollection 2024 Sep.

¹ Department of Anaesthesiology and Intensive Care, Paris-Saclay University, Paul Brousse Hospital, Assistance Publique Hôpitaux de Paris, Villejuif, France.
² Outcomes Research Consortium, Cleveland, OH, USA.
³ Cell Death and Inflammation Unit, VIB-UGent Center for Inflammation Research (IRC), Ghent, Belgium.
⁴ Department of Anaesthesiology, Chirec Delta Hospital, Brussels, Belgium.
⁵ Department of General Surgery, Chirec Delta Hospital, Brussels, Belgium.
⁶ Department of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.

No abstract available

Keywords: Nociception-antinociception balance; nociception monitoring; opioid free anaesthesia.

References

1. Clanet M., Touihri K., El Haddad C., et al. Effect of opioid-free versus opioid-based strategies during multimodal anaesthesia on postoperative morphine consumption after bariatric surgery: a randomised double-blind clinical trial. BJA Open. 2024;9 - PMC - PubMed
1. Perrin L., Bisdorff M., Saxena S., et al. Predicting personalised remifentanil effect site concentration for surgical incision using the nociception level index: a prospective calibration and validation study. Eur J Anaesthesiol. 2022;39:918–927. - PubMed
1. Meijer F.S., Martini C.H., Broens S., et al. Nociception-guided versus standard care during remifentanil-propofol anesthesia: a randomized controlled trial. Anesthesiology. 2019;130:745–755. - PubMed
1. Meijer F., Honing M., Roor T., et al. Reduced postoperative pain using nociception level-guided fentanyl dosing during sevoflurane anaesthesia: a randomised controlled trial. Br J Anaesth. 2020;125:1070–1078. - PMC - PubMed
1. Coeckelenbergh S., Doria S., Patricio D., et al. Effect of dexmedetomidine on Nociception Level Index-guided remifentanil antinociception: a randomised controlled trial. Eur J Anaesthesiol. 2021;38:524–533. - PubMed