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. 2024 May 20;4(3):142-146.
doi: 10.1016/j.aopr.2024.05.002. eCollection 2024 Aug-Sep.

The efficacy of an irrigating eyelid retractor-facilitated ocular rinse on MMP-9 expression and dry eye disease

Natasha Mayer  1 , Srinivas Sai A Kondapalli  2 , Nandini Venkateswaran  3 , Hajirah N Saeed  4
Affiliations

The efficacy of an irrigating eyelid retractor-facilitated ocular rinse on MMP-9 expression and dry eye disease

Natasha Mayer et al. Adv Ophthalmol Pract Res. .
No abstract available

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Figures

Fig. 1
Fig. 1
Irrigating eyelid retractor illustrating ports as the distal end aimed at the palpebral conjunctiva, conjunctival fornix and bulbar conjunctiva (top, middle, bottom, respectively).
Fig. 2
Fig. 2
Illustration of the irrigating eyelid retractor under the upper eyelid with arrows (red) demonstrating the direction of fluid aimed simultaneously at the palpebral conjunctiva, conjunctival fornix and bulbar conjunctiva.
Fig. 3
Fig. 3
Digital photograph of ImflammaDry MMP-9 immunoassay. Blue lines indicate control condition and red lines indicate MMP-9 detection. Red line intensity indicates relative amount of MMP-9 detected with more intense red lines revealing higher MMP-9 expression.
Fig. 4
Fig. 4
MMP-9 grading as compared to baseline for control and device rinse groups for 3 hours post-rinse. Grey bars indicate baseline MMP-9 expression reported as the average grade of 4 independent graders. No significant difference (ns) was observed between baseline groups (P ​> ​0.05). Error bars indicate standard deviation and columns are labeled with the average graded value for each group. Both control and device groups showed a reduction in MMP-9 expression (P ​= ​0.0334 and P ​< ​0.0001, respectively) compared to baseline. Combination effects of time and protocol reveal significant reduction in MMP-9 post-rinse in the device group as compared to the control condition (P ​< ​0.0001).
See this image and copyright information in PMC

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