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. 1985 Nov;50(2):586-7.
doi: 10.1128/iai.50.2.586-587.1985.

Plasmid-cured Salmonella enteritidis AL1192 as a candidate for a live vaccine

M Nakamura, S Sato, T Ohya, S Suzuki, S Ikeda, T Koeda

Plasmid-cured Salmonella enteritidis AL1192 as a candidate for a live vaccine

M Nakamura et al. Infect Immun. 1985 Nov.

Abstract

We report the immunizing capacity of Salmonella enteritidis AL1192, a strain that has been cured of a 36-megadalton plasmid, to protect ddY mice against subsequent challenge with virulent salmonellas. This strain, which was given subcutaneously at a dose of 10(6) organisms, provided significant protection against oral, subcutaneous, or intraperitoneal challenge by virulent wild-type strains of not only S. enteritidis, but also S. dublin, S. naestved, and S. typhimurium.

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