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. 2024 Jan 19;14(2):230-235.
doi: 10.4103/tjo.TJO-D-23-00150. eCollection 2024 Apr-Jun.

Ectopia Lentis: Clinical profiles in a large cohort of children from a Tertiary Eye Care network in India

Manjushree Bhate  1 , Anthony Vipin Das  2 , Ramesh Kekunnaya  1 , Virender Sachdeva  3 , Muralidhar Ramappa  4 , Vivek Warkad  5 , Debasmita Majhi  5
Affiliations

Ectopia Lentis: Clinical profiles in a large cohort of children from a Tertiary Eye Care network in India

Manjushree Bhate et al. Taiwan J Ophthalmol. .

Abstract

Purpose: To study the clinical presentations, visual, and refractive profiles of children with congenital ectopia lentis in a large cohort of patients from a tertiary eye care network in India.

Materials and methods: A retrospective review of electronic medical records from December 2012 to December 2020 was conducted. Two hundred and ninety-seven consecutive children ≤18 years of age at presentation were identified and analyzed for demographic details, patient distribution, lens subluxation, visual, and refractive profiles before and after the interventions.

Results: Five hundred and ninety-four eyes of 297 (male 56%; n = 166) patients were analyzed. The mean age at presentation was 8.74 ± 3.89. Best-corrected visual acuity (BCVA) at presentation ranged from 0.3 logMAR to 3.5 logMAR; (Snellen: 6/9 - close to face [CF]) (mean 0.89 ± 0.68). High myopia (n = 201; 33.83%) and mild astigmatism (n = 340; 57.23%) were more frequent. Temporal (n = 108; 18.18%) subluxation was most common followed by superior. Lensectomy with limited vitrectomy was performed in 243 eyes of 127 patients (40.90%). Median preoperative BCVA was 1.0 (range: 0.3-3.5 logMAR; 20/40 - CF). Median postoperative BCVA was 0.5 logMAR (6/18) in the pseudophakic group and 0.6 logMAR (6/24) in the aphakic group. Spherical equivalent in myopic children reduced from -12.06 ± 6.84D to -1.57D (-0.25D to - 5.5D) in the pseudophakic group and +9.3D (+5.5D to 15.5D) in the aphakic group.

Conclusion: This study is a large cohort of children presenting with ectopia lentis. Following intervention, an improvement in the median BCVA and refractive correction was noted in the entire cohort.

Keywords: Astigmatism; Marfan’s syndrome; ectopia lentis; lensectomy; visual rehabilitation.

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Conflict of interest statement

The authors declare that there are no conflicts of interest in this paper.

Figures

Figure 1
Figure 1
Direction of lens subluxation
Figure 2
Figure 2
Ocular co-morbidities
See this image and copyright information in PMC

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