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Case Reports
. 2024 Jul;24(4):100229.
doi: 10.1016/j.clinme.2024.100229. Epub 2024 Jul 17.

Pure red cell aplasia secondary to erythropoietin therapy

Gwenno Mair Edwards  1 , Abdulfattah A Alejmi  2
Affiliations
Case Reports

Pure red cell aplasia secondary to erythropoietin therapy

Gwenno Mair Edwards et al. Clin Med (Lond). 2024 Jul.

Abstract

We report a case series of two patients with chronic kidney disease (CKD) who developed erythropoietin-induced pure red cell aplasia following a change in erythropoietin preparation. Both patients responded well to immunosuppressive treatments, but unfortunately developed severe infections as a result of being immunosuppressed.

Keywords: Erythropoietin; Pure red cell aplasia.

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Conflict of interest statement

Declaration of competing interest None.

References

    1. Pollock C., Johnson D., Horl W., et al. Pure red cell aplasia induced by erythropoiesis-stimulating agents. Clin J Am Soc Nephrol. 2008;3:193–199. - PubMed
    1. Bennett C., Luminari S., Nissenson A., et al. Pure red-cell aplasia and epoetin therapy. N Engl J Med. 2004;351:1403–1408. - PubMed
    1. Cournoyer D., Toffelmire E., Wells G., et al. Anti-erythropoietin antibody-mediated pure red cell aplasia after treatment with recombinant erythropoietin prodcuts: recommendations for minimization of risk. J Am Soc Nephrol. 2004;15(10):2728. - PubMed
    1. Badiu I., Diena D., Guida G., Ferrando C., Rapezzi D., Besso L. Cutaneous allergic reaction correlates with anti-erythropoietin antibodies in dialysis patient developing pure red cell aplasia. Clin Case Rep. 2022;10:e05554. doi: 10.1002/ccr3.5554. - DOI - PMC - PubMed
    1. Verhelst D., Rossert J., Casadevall N., et al. The Lancet. 2004;363(9423):1768–1771. doi: 10.1016/S0140-6736(04)16302-2. - DOI - PubMed

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