The enigmatic AHRR: beyond aryl hydrocarbon receptor repression

Affiliations

¹ Biology Department, MS-32, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.
² Department of Environmental Health, Housman R-408, Boston University School of Public Health, 72 E. Concord St, Boston, MA 02118, USA.

Editorial

Mark E Hahn et al. J Leukoc Biol. 2024.

. 2024 Nov 4;116(5):915-918.

doi: 10.1093/jleuko/qiae163.

¹ Biology Department, MS-32, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.
² Department of Environmental Health, Housman R-408, Boston University School of Public Health, 72 E. Concord St, Boston, MA 02118, USA.

Abstract

Discussion on the many roles of AHR Repressor (AHRR) in intestinal immune homeostasis

Keywords: AHR repressor; aryl hydrocarbon receptor; eosinophils; intestine; mucosal immunology.

Conflict of interest statement. None declared.

The AHR repressor limits expression of antimicrobial genes but not AHR-dependent genes in intestinal eosinophils.
Weighardt H, Shapiro M, Mayer M, Förster I, Stockinger B, Diny NL. Weighardt H, et al. J Leukoc Biol. 2024 Jul 25;116(2):369-378. doi: 10.1093/jleuko/qiae105. J Leukoc Biol. 2024. PMID: 38701199 Free PMC article.

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