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. 2024 Sep;79(3):631-635.
doi: 10.1002/jpn3.12323. Epub 2024 Jul 20.

Utilization and impact of esophageal string testing in children with eosinophilic esophagitis: A 1 year experience

Laura A Quinn  1 , Rachel Andrews  1 , Maureen Bauer  2 , Nathalie Nguyen  1
Affiliations

Utilization and impact of esophageal string testing in children with eosinophilic esophagitis: A 1 year experience

Laura A Quinn et al. J Pediatr Gastroenterol Nutr. 2024 Sep.

Abstract

The 1-h esophageal string test (EST) is a minimally invasive test that can be used to monitor eosinophilic esophagitis (EoE) disease activity and guide treatment without endoscopy. We aimed to describe the real-world utilization and impact of EST on the care of children with EoE over the first year this was used at our center. Between 12/1/2022 and 11/30/2023, 39 ESTs were successful in 45 attempts (87% completion rate) in 31 patients. Five patients underwent multiple ESTs. Adverse events during the EST included vomiting. Reasons for failure to complete the EST (13%, n = 6) were patients could not swallow the capsule (n = 5) and vomiting (n = 1). EST was used to assess EoE without the need for endoscopy in 95% (n = 37) of cases. Treatment approach varied based on whether the EST indicated active (38.5%) or inactive (61.5%) EoE. The EST is a well-tolerated minimally invasive disease monitoring tool for patients with EoE.

Keywords: disease activity; minimally invasive; nonendoscopic.

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