Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jul 30;2(3):139-147.
doi: 10.1016/j.jncc.2022.07.004. eCollection 2022 Sep.

Lung cancer incidence and mortality in China: Updated statistics and an overview of temporal trends from 2000 to 2016

Rongshou Zheng  1 , Siwei Zhang  1 , Shaoming Wang  1 , Ru Chen  1 , Kexin Sun  1 , Hongmei Zeng  1 , Li Li  1 , Wenqiang Wei  1 , Jie He  2
Affiliations

Lung cancer incidence and mortality in China: Updated statistics and an overview of temporal trends from 2000 to 2016

Rongshou Zheng et al. J Natl Cancer Cent. .

Abstract

Background: Updated systematic statistics on lung cancer are the underpinning cornerstones for formulating prevention and control strategies for the disease. The incidence and mortality data of lung cancer in China in 2016 were estimated, and also used to analyze the temporal trends of lung cancer from 2000 up to 2016 in this study.

Methods: The burden of lung cancer in China in 2016 was estimated using data from 487 cancer registries, which were abstracted from the database of the National Cancer Center of China (NCC). The temporal trends were estimated with the data of 2000 to 2016 from 22 cancer registries.

Results: About 828,100 new lung cancer cases and 657,000 lung cancer deaths were estimated in China in 2016. The crude incidence and mortality rates in the eastern region were the highest nationwide. The incidence and mortality of lung cancer increased with age, and most of the new cases occurred in the age group of over 60 years. The age-standardized incidence increased by about 0.8% per year during 2000 to 2016, especially in woman, whose annual increase rate reached 2.1%. The age-standardized mortality rate decreased by about 0.6% per year, with a decrease of 1.3% per year in urban areas and an increase of 2.3% per year in rural areas. The numbers of new cases and deaths increased by 162.6% and 123.6%, respectively, during 2000 to 2016, which can be explained mainly by the change of the age structure.

Conclusions: The burden of lung cancer is serious in China, and increased especially rapidly for women in rural areas. The disease is expected to threaten the lives of more people in the future due to factors such as aging and population growth. Lung cancer prevention and control strategies and resources should be leveraged toward women and rural areas in the future.

Keywords: Cancer registry; China; Lung cancer; Temporal trends.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflict of interests.

Figures

Fig 1
Fig. 1
Numbers of new cases or deaths and age-specific rate of lung cancer by age groups in China, 2016 (A) Incidence. (B) Mortality.
Fig 2
Fig. 2
Birth cohort specific incidence rates for lung cancer by gender and areas. (A) Male. (B) Female. (C) Urban. (D) Rural.
Fig 3
Fig. 3
Birth cohort specific mortality rates for lung cancer by gender and areas. (A) Male. (B) Female. (C) Urban. (D) Rural.
Fig 4
Fig. 4
Trends of age-specific incidence for lung cancer by gender and areas, 2000-2016. (A) Male. (B) Female. (C) Urban. (D) Rural.
Fig 5
Fig. 5
Trends of age-specific mortality for lung cancer by gender and areas, 2000-2016. (A) Male. (B) Female. (C) Urban. (D) Rural.
See this image and copyright information in PMC

References

    1. Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424. - PubMed
    1. Kabir Z, Bennett K, Clancy L. Lung cancer and urban air-pollution in Dublin: a temporal association? Ir Med J. 2007;100(2):367–369. - PubMed
    1. Loomis D, Grosse Y, Lauby-Secretan B, et al. The carcinogenicity of outdoor air pollution. Lancet Oncol. 2013;14(13):1262–1263. - PubMed
    1. Moolgavkar SH, Holford TR, Levy DT, et al. Impact of reduced tobacco smoking on lung cancer mortality in the United States during 1975–2000. J Natl Cancer Inst. 2012;104(7):541–548. - PMC - PubMed
    1. Pesch B, Kendzia B, Gustavsson P, et al. Cigarette smoking and lung cancer—relative risk estimates for the major histological types from a pooled analysis of case–control studies. Int J Cancer. 2012;131(5):1210–1219. - PMC - PubMed

LinkOut - more resources