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Case Reports
. 2024 Jan-Jun;18(1):144-147.
doi: 10.4103/ajts.ajts_164_21. Epub 2022 Sep 28.

Outcome of pregnancy in sickle cell anemia patients with COVID-19 infection

Vaidyanathan Gowri  1 , Tamima Al Dughaishi  1 , Deepti Geetha  1 , Marwa Al Riyami  1 , Radhiya Alburaidi  2 , Salam Al Kindi  1
Affiliations
Case Reports

Outcome of pregnancy in sickle cell anemia patients with COVID-19 infection

Vaidyanathan Gowri et al. Asian J Transfus Sci. 2024 Jan-Jun.

Abstract

Sickle cell anemia (SCA) is a multisystem disease, associated with increased risk for infection and thromboembolic disease, and pregnancy is a stressor for patients with SCA. In general, coronavirus disease 2019 (COVID-19) infection in SCA is associated with a favorable outcome. Literature of pregnancy in SCA with COVID is scarce. We report a case series study of pregnant women with SCA, who are confirmed positive for COVID-19 from May 2020 to March 2021. These patients showed generally mild-to-moderate disease and presented predominantly with fever and painful crisis. They showed a significant drop in Hb from baseline, and they received low-molecular-weight heparin prophylaxis (LMWH) and blood transfusion. The outcome of pregnancy is satisfactory, although the mean birth weight was significantly lower than that reported from the same SCA population.

Keywords: Coronavirus disease 2019; pregnancy; severe acute respiratory syndrome coronavirus 2; sickle cell anemia.

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Conflict of interest statement

There are no conflicts of interest.

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