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Editorial
. 2025 Jan;31(1):281-285.
doi: 10.3350/cmh.2024.0568. Epub 2024 Jul 23.

UBE2S: A novel driver of HIF-1alpha-induced metabolic reprogramming in hepatocellular carcinoma: Editorial on "UBE2S promotes glycolysis in hepatocellular carcinoma by enhancing E3 enzyme-independent polyubiquitination of VHL"

Martina Mang Leng Lei  1 , Terence Kin Wah Lee  1   2
Affiliations
Editorial

UBE2S: A novel driver of HIF-1alpha-induced metabolic reprogramming in hepatocellular carcinoma: Editorial on "UBE2S promotes glycolysis in hepatocellular carcinoma by enhancing E3 enzyme-independent polyubiquitination of VHL"

Martina Mang Leng Lei et al. Clin Mol Hepatol. 2025 Jan.
No abstract available

Keywords: Glycolysis; HIF-1alpha; Hepatocellular carcinoma; UBE2S.

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Conflict of interest statement

Conflicts of Interest

The authors have no conflicts to disclose.

Figures

Figure 1.
Figure 1.
Schematic representation of the role of E2F2/UBE2S/VHL in regulating HIF-1α-driven glycolysis in HCC. VHL, von Hippel– Lindau tumor suppressor; HCC, hepatocellular carcinoma.
See this image and copyright information in PMC

Comment on

  • Clin Mol Hepatol. 31:cmh.2024.0236.

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