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Clinical Trial
. 1985;13(5):209-12.
doi: 10.1007/BF00261577.

Comparison between continuous and intermittent administration of Estracyt in the treatment of carcinoma of the prostate

W Vahlensieck, G Wegner, H D Lehmann, G Franzen, L Steffens, S Wählby
Clinical Trial

Comparison between continuous and intermittent administration of Estracyt in the treatment of carcinoma of the prostate

W Vahlensieck et al. Urol Res. 1985.

Abstract

Ninety-five patients with prostatic carcinoma, stages A-D and of all histological grades were randomized between a continuous and an intermittent treatment regimen of Estracyt (estramustine phosphate). 77 patients were evaluated (46 with continuous and 31 with intermittent therapy). Remissions were seen in 13 (28%) and (13%), respectively. Stable disease was recorded in 30 (65%) and 24 (77%), respectively. Progression experienced 3 (6%) and 3 (10%) respectively. 19% were unable to continue therapy due to intolerable gastrointestinal side effects (7 patients receiving continuous and 8 patients receiving intermittent therapy).

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