Hypothalamic monoamine contents in endotoxin fever of new-born guinea pigs and kittens
- PMID: 390425
- DOI: 10.1016/0304-3940(79)90008-9
Hypothalamic monoamine contents in endotoxin fever of new-born guinea pigs and kittens
Abstract
In new-born guinea pigs and kittens Escherichia coli endotoxin did not significantly modify the hypothalamic level of either norepinephrine (NE) or 5-hydroxytryptamine (5-HT). The hypothalamic 5-hydroxyindoleacetic acid (5-HIAA) content was significantly elevated in endotoxin-treated animals, but this elevation was confined to a period following the endotoxin injections by about 60 min in guinea pigs and 75-90 min in kittens.
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