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Case Reports
. 2024 Jul 23;111(4):710-712.
doi: 10.4269/ajtmh.24-0018. Print 2024 Oct 2.

Post-Kala-Azar Dermal Leishmaniasis

Apoorva Sharma  1 , Anuradha Bishnoi  1 , Davinder Parsad  1
Affiliations
Case Reports

Post-Kala-Azar Dermal Leishmaniasis

Apoorva Sharma et al. Am J Trop Med Hyg. .
No abstract available

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Conflict of interest statement

Authors’ contributions: A. Sharma: conceptualization, writing—original (lead), writing—revision (lead). A Bishnoi: writing—original (equal), writing—revision (equal). D. Parsad: conceptualization, writing—original (equal), writing—revision (equal), supervision.

Figures

Figure 1.
Figure 1.
Multiple, well-defined, non-scaly, normoesthetic, hypopigmented patches ranging in size from 3 × 5 cm to 10 × 15 cm over the trunk, neck, and back.
Figure 2.
Figure 2.
Multiple discrete, skin-colored to slightly erythematous papulonodular lesions on the central part of the face, ears, upper limbs, and back, ∼1 to 2 cm. These lesions covered the nose and mouth area of the face, which may be an important clinical clue for the diagnosis of post-kala-azar dermal leishmaniasis.
Figure 3.
Figure 3.
(A and B) Skin biopsies showed presence of Grenz zone and band-like infiltrate in papillary dermis. Dermis showed mixed inflammatory infiltrates comprising of lymphocytes, histiocytes, plasma cells, and neutrophils. There was presence of well-formed epithelioid cell granulomas with scattered multinucleated giant cells. The histiocytes showed intractoplasmic amastigote forms of leishmania (hematoxylin and eosin stain, 40× and 100×) (C) Giemsa stain showed presence of Leishmanin–Donovan bodies (100×).
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References

    1. Hasnain G, Shomik MS, Ghosh P, Rashid MO, Hossain S, Homano S, Mondal D, 2016. Post-kala-azar dermal leishmaniasis without previous history of visceral leishmaniasis. Am J Trop Med Hyg 95: 1383–1385. - PMC - PubMed
    1. Kumar A, Singh VK, Tiwari R, Madhukar P, Rajneesh, Kumar S, Gautam V, Engwerda C, Sundar S, Kumar R, 2023. Post kala-azar dermal leishmaniasis in the Indian sub-continent: Challenges and strategies for elimination. Front Immunol 14: 1236952. - PMC - PubMed
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