Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2024 Jul 23;111(4):710-712.
doi: 10.4269/ajtmh.24-0018. Print 2024 Oct 2.

Post-Kala-Azar Dermal Leishmaniasis

Apoorva Sharma  1 , Anuradha Bishnoi  1 , Davinder Parsad  1
Affiliations
Case Reports

Post-Kala-Azar Dermal Leishmaniasis

Apoorva Sharma et al. Am J Trop Med Hyg. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Authors’ contributions: A. Sharma: conceptualization, writing—original (lead), writing—revision (lead). A Bishnoi: writing—original (equal), writing—revision (equal). D. Parsad: conceptualization, writing—original (equal), writing—revision (equal), supervision.

Figures

Figure 1.
Figure 1.
Multiple, well-defined, non-scaly, normoesthetic, hypopigmented patches ranging in size from 3 × 5 cm to 10 × 15 cm over the trunk, neck, and back.
Figure 2.
Figure 2.
Multiple discrete, skin-colored to slightly erythematous papulonodular lesions on the central part of the face, ears, upper limbs, and back, ∼1 to 2 cm. These lesions covered the nose and mouth area of the face, which may be an important clinical clue for the diagnosis of post-kala-azar dermal leishmaniasis.
Figure 3.
Figure 3.
(A and B) Skin biopsies showed presence of Grenz zone and band-like infiltrate in papillary dermis. Dermis showed mixed inflammatory infiltrates comprising of lymphocytes, histiocytes, plasma cells, and neutrophils. There was presence of well-formed epithelioid cell granulomas with scattered multinucleated giant cells. The histiocytes showed intractoplasmic amastigote forms of leishmania (hematoxylin and eosin stain, 40× and 100×) (C) Giemsa stain showed presence of Leishmanin–Donovan bodies (100×).
See this image and copyright information in PMC

References

    1. Hasnain G, Shomik MS, Ghosh P, Rashid MO, Hossain S, Homano S, Mondal D, 2016. Post-kala-azar dermal leishmaniasis without previous history of visceral leishmaniasis. Am J Trop Med Hyg 95: 1383–1385. - PMC - PubMed
    1. Kumar A, Singh VK, Tiwari R, Madhukar P, Rajneesh, Kumar S, Gautam V, Engwerda C, Sundar S, Kumar R, 2023. Post kala-azar dermal leishmaniasis in the Indian sub-continent: Challenges and strategies for elimination. Front Immunol 14: 1236952. - PMC - PubMed
    1. Faleiro RJ, Kumar R, Hafner LM, Engwerda CR, 2014. Immune regulation during chronic visceral leishmaniasis. PLoS Negl Trop Dis 8: e2914. - PMC - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources