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Case Reports
. 2024 Jul 23;111(4):707-709.
doi: 10.4269/ajtmh.24-0133. Print 2024 Oct 2.

Disseminated Blastomycosis

Affiliations
Case Reports

Disseminated Blastomycosis

Ashton D Hall et al. Am J Trop Med Hyg. .
No abstract available

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Conflict of interest statement

Authors’ contributions: A. D. Hall, original draft, Figures 1 to 5, and revisions; K. Patel, reviewing and editing; M. B. Burch, reviewing, editing, and Figure 4; L. M. Rotert, reviewing and editing.

Figures

Figure 1.
Figure 1.
Fourth toe of the left foot at initial presentation (A), readmission (B), and outpatient follow-up at 3 months (C). Progressively worsening ulceration of the dorsal aspect with irregularly raised hyperkeratotic tissue, serous drainage, and eventual scarring.
Figure 2.
Figure 2.
Elevated ulcerative lesion of the right lower lip at initial presentation (A), readmission (B), and outpatient follow up at 3 months (C) with minimal scarring.
Figure 3.
Figure 3.
Psoriasiform plaque of the right elbow at initial presentation (A) and readmission (B). An assortment of brown to pink, scaly and verrucous, slightly fluctuant hyperkeratotic plaques of the left midback (C), left and right inner leg (D and E), and left calf (F) on initial presentation. Follow-up images were not available.
Figure 4.
Figure 4.
(A) Computed tomography chest scan on readmission showing focal scarring with bronchiectasis in the inferior left upper lobe. (B) Maximum intensity projection image showing multiple scattered lung nodules in both upper lobes. (C) Right axillary lymphadenopathy measuring 3.2 × 2.3 cm with possible necrosis. Courtesy of M. B. Burch at the University of Cincinnati.
Figure 5.
Figure 5.
(A) Skin biopsy specimen with periodic acid-Schiff stain with diastase at 40× magnification showing broad-based budding yeasts of 10 μm surrounded by neutrophils in an epidermal microabscess. Courtesy of K. E. Spicknall at the University of Cincinnati. (B) Microscopic image of Blastomyces dermatitidis stained with lactophenol aniline blue showing the characteristic round or oval single conidia at the apex of a conidiophore. (C) Blastomyces dermatitidis growing on inhibitory mold agar at 25°C. Courtesy of N. L. Wengenack and the Mayo Clinic Mycology Laboratory, where the patient’s sample was processed.

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References

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