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Comment
. 2024 Sep;23(9):659.
doi: 10.1038/d41573-024-00122-3.

Molecular glue degrader for sickle cell disease

Katie Kingwell
Comment

Molecular glue degrader for sickle cell disease

Katie Kingwell. Nat Rev Drug Discov. 2024 Sep.
No abstract available

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Comment on

  • A molecular glue degrader of the WIZ transcription factor for fetal hemoglobin induction.
    Ting PY, Borikar S, Kerrigan JR, Thomsen NM, Aghania E, Hinman AE, Reyes A, Pizzato N, Fodor BD, Wu F, Belew MS, Mao X, Wang J, Chitnis S, Niu W, Hachey A, Cobb JS, Savage NA, Burke A, Paulk J, Dovala D, Lin J, Clifton MC, Ornelas E, Ma X, Ware NF, Sanchez CC, Taraszka J, Terranova R, Knehr J, Altorfer M, Barnes SW, Beckwith REJ, Solomon JM, Dales NA, Patterson AW, Wagner J, Bouwmeester T, Dranoff G, Stevenson SC, Bradner JE. Ting PY, et al. Science. 2024 Jul 5;385(6704):91-99. doi: 10.1126/science.adk6129. Epub 2024 Jul 4. Science. 2024. PMID: 38963839

References

    1. Ting, P. Y. et al. A molecular glue degrader of the WIZ transcription factor for fetal hemoglobin induction. Science 385, 91–99 (2024) - PubMed - DOI

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