Breaking the borders of wakefulness and sleep-the search for novel biomarkers to quantify sleepiness

David R Schreier^{1

2

3

4

5}, Veronique E C Vael^{5

6}, Gert Jan Lammers^{5

6}

Affiliations

¹ Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
² Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA.
³ Center for Neurotechnology and Neurorecovery, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
⁴ Department of Neurology, Inselspital, Bern University Hospital, and University of Bern, Switzerland.
⁵ Stichting Epilepsie Instellingen Nederland (SEIN), Sleep-Wake Centre, Heemstede, The Netherlands.
⁶ Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands.

Editorial

David R Schreier et al. Sleep. 2024.

. 2024 Dec 11;47(12):zsae167.

doi: 10.1093/sleep/zsae167.

David R Schreier^{1

2

3

4

5}, Veronique E C Vael^{5

6}, Gert Jan Lammers^{5

6}

¹ Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
² Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA.
³ Center for Neurotechnology and Neurorecovery, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
⁴ Department of Neurology, Inselspital, Bern University Hospital, and University of Bern, Switzerland.
⁵ Stichting Epilepsie Instellingen Nederland (SEIN), Sleep-Wake Centre, Heemstede, The Netherlands.
⁶ Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands.

No abstract available

Comment on

Novel biomarkers derived from the Maintenance of Wakefulness Test as predictors of sleepiness and response to treatment.
Tracey B, Culp M, Fabregas S, Mignot E, Buhl DL, Volfson D. Tracey B, et al. Sleep. 2024 Dec 11;47(12):zsae148. doi: 10.1093/sleep/zsae148. Sleep. 2024. PMID: 38954525 Free PMC article. Clinical Trial.

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