Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Aug 1;44(8):e53-e55.
doi: 10.1097/IAE.0000000000004134.

Reply

Affiliations

Reply

Wataru Matsumiya et al. Retina. .

Abstract

We wrote the letter in response to the insightful comments made by Dr. Vassallo J regarding our recently published study, “Association of Oral Montelukast with Reduced Odds of Developing Exudative Age-Related Macular Degeneration.” Our study underscored the potential treatment for AMD through managing mast cell activation.

PubMed Disclaimer

Comment on

References

    1. Matsumiya W, Karaca I, Pham BH et al. ASSOCIATION OF ORAL MONTELUKAST WITH REDUCED ODDS OF DEVELOPING EXUDATIVE AGE-RELATED MACULAR DEGENERATION. Retina 2023; 43:1914–1921. - PubMed
    1. Knickelbein JE, Chan CC, Sen HN et al. Inflammatory Mechanisms of Age-related Macular Degeneration. Int Ophthalmol Clin 2015; 55:63–78. - PMC - PubMed
    1. Bhutto IA, McLeod DS, Jing T et al. Increased choroidal mast cells and their degranulation in age-related macular degeneration. Br J Ophthalmol 2016; 100:720–726. - PMC - PubMed
    1. Kim BJ, Mastellos DC, Li Y et al. Targeting complement components C3 and C5 for the retina: Key concepts and lingering questions. Prog Retin Eye Res 2021; 83:100936. - PMC - PubMed
    1. Schäfer B, Piliponsky AM, Oka T et al. Mast cell anaphylatoxin receptor expression can enhance IgE-dependent skin inflammation in mice. J Allergy Clin Immunol 2013; 131:541–548.e541–549. - PMC - PubMed