Introductory comments about the special series of thrombotic microangiopathy
- PMID: 39049904
- PMCID: PMC11268838
- DOI: 10.21037/aob-24-6
Introductory comments about the special series of thrombotic microangiopathy
Keywords: ADAMTS13; Thrombotic thrombocytopenic purpura (TTP); complement; thrombotic microangiopathy; von Willebrand factor (VWF).
Conflict of interest statement
The author has completed the ICMJE uniform disclosure form (available at https://aob.amegroups.org/article/view/10.21037/aob-24-6/coif). The series “Thrombotic Thrombocytopenic Purpura” was commissioned by the editorial office without any funding or sponsorship. X.L.Z. served as the unpaid Guest Editor of the series and serves as an unpaid editorial board member of the Annals of Blood from March 2024 to February 2026. X.L.Z. is a consultant for Alexion, Apollo, Argenx, BioMedica Diagnostics, GC Biopharma, Kyowa Kirin, Sanofi, and Takeda, as well as a co-founder of Clotsolution. The author has no other conflicts of interest to declare.
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References
-
- Moschcowitz E Hyaline thrombosis of the terminal arterioles and capillaries: a hitherto undescribed disease. Proc N Y Pathol Soc 1924;24:21–4.
-
- Amorosi EL, Ultmann JE. Thrombotic thrombocytopenic purpura: report of 16 cases and review of the literature. Medicine 1966;45:139–60.
-
- Ansell J, Beaser RS, Pechet L. Thrombotic thrombocytopenic purpura fails to respond to fresh frozen plasma infusion. Ann Intern Med 1978;89:647–8. - PubMed
-
- Moake JL, Rudy CK, Troll JH, et al. Unusually large plasma factor VIII: von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura. N Engl J Med 1982;307:1432–5. - PubMed
-
- Furlan M, Robles R, Solenthaler M, et al. Deficient activity of von Willebrand factor-cleaving protease in chronic relapsing thrombotic thrombocytopenic purpura. Blood 1997;89:3097–103. - PubMed
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