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. 2024 Jul 15;12(14):1407.
doi: 10.3390/healthcare12141407.

Early Cholecystectomy after Endoscopic Retrograde Cholangiopancreatography Is Feasible and Safe

Çağrı Büyükkasap  1 , Deniz Algan  2 , Nigar Balakji  2 , Onur Metindoğan  1 , Ali Karataş  3 , Aydın Yavuz  1 , Hüseyin Göbüt  1 , Kürşat Dikmen  1 , Murat Kekilli  3 , Hasan Bostancı  1
Affiliations

Early Cholecystectomy after Endoscopic Retrograde Cholangiopancreatography Is Feasible and Safe

Çağrı Büyükkasap et al. Healthcare (Basel). .

Abstract

Laparoscopic cholecystectomy (LC) following endoscopic retrograde cholangiopancreatography (ERCP) is the preferred treatment for cholelithiasis with common bile duct stones. However, the optimal timing of LC after ERCP remains controversial. This study aimed to identify the ideal time interval between ERCP and LC. Data from patients who underwent LC after ERCP between November 2016 and August 2022 were retrieved from the electronic medical information system. The patients were categorized into early cholecystectomy (within 72 h of ERCP) and delayed cholecystectomy (after 72 h). The impact of the time interval between ERCP and LC on perioperative outcomes was analyzed. A total of 197 patients were included in the study, with 45 undergoing early cholecystectomy and 152 undergoing delayed cholecystectomy. No significant differences in the preoperative characteristics or operative morbidity were observed between the groups (p = 0.286). However, a significant correlation was found between the time interval from ERCP to LC and the total length of stay (r = -350, p < 0.001). The findings suggest that early cholecystectomy after ERCP is feasible and safe, and performing LC within the first 72 h does not adversely affect postoperative outcomes.

Keywords: ERCP; choledocholithiasis; early cholecystectomy; laparoscopic cholecystectomy; perioperative outcomes.

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Conflict of interest statement

The authors declare no conflicts of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.

Figures

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Figure 1
Flowchart of research strategy.
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References

    1. Buxbaum J.L., Abbas Fehmi S.M., Sultan S., Fishman D.S., Qumseya B.J., Cortessis V.K., Schilperoort H., Kysh L., Matsuoka L., Yachimski P., et al. ASGE guideline on the role of endoscopy in the evaluation and management of choledocholithiasis. Gastrointest. Endosc. 2019;89:1075–1105.e5. doi: 10.1016/j.gie.2018.10.001. - DOI - PMC - PubMed
    1. Boni L., Huo B., Alberici L., Ricci C., Tsokani S., Mavridis D., Amer Y.S., Andreou A., Berriman T., Donatelli G., et al. EAES rapid guideline: Updated systematic review, network meta-analysis, CINeMA and GRADE assessment, and evidence-informed European recommendations on the management of common bile duct stones. Surg. Endosc. 2022;36:7863–7876. doi: 10.1007/s00464-022-09662-4. - DOI - PubMed
    1. Muhammedoğlu B., Kale I.T. Comparison of the safety and efficacy of single-stage endoscopic retrograde cholangiopancreatography plus laparoscopic cholecystectomy versus two-stage ERCP followed by laparoscopic cholecystectomy six-to-eight weeks later: A randomized controlled trial. Int. J. Surg. 2020;76:37–44. doi: 10.1016/j.ijsu.2020.02.021. - DOI - PubMed
    1. Mallick R., Rank K., Ronstrom C., Amateau S.K., Arain M., Attam R., Freeman M.L., Harmon J.V. Single-session laparoscopic cholecystectomy and ERCP: A valid option for the management of choledocholithiasis. Gastrointest. Endosc. 2016;84:639–645. doi: 10.1016/j.gie.2016.02.050. - DOI - PubMed
    1. Costi R., Gnocchi A., Di Mario F., Sarli L. Diagnosis and management of choledocholithiasis in the golden age of imaging, endoscopy and laparoscopy. World J. Gastroenterol. 2014;20:13382–13401. doi: 10.3748/wjg.v20.i37.13382. - DOI - PMC - PubMed

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