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Observational Study
. 2024 Jul 26;103(30):e38915.
doi: 10.1097/MD.0000000000038915.

Correlation in retinal thickness and macular retina plus choroidal microcirculation in pediatric myopia

Fang Cheng  1 , Dan Tian  2
Affiliations
Observational Study

Correlation in retinal thickness and macular retina plus choroidal microcirculation in pediatric myopia

Fang Cheng et al. Medicine (Baltimore). .

Abstract

To analyze the relationship in retinal thickness, macula retina and choroidal microcirculation in pediatric patients with myopia. Pediatric patients with high myopia (high myopia group, n = 30, 60 eyes) and pediatric patients with low to moderate myopia (low myopia group, n = 30, 60 eyes) admitted to our hospital from January 2021 to January 2022 were randomly selected as the study subjects. Retinal thickness, the blood density of retina, and the blood density of the choroid were collected in each area of the macula by taking optical coherence tomography (OCT) and OCT angiography (OCTA). Pearson correlation analysis was conducted to compare the results from the 2 groups. Outer retinal thickness showed a weak positive correlation with Superficial vascular complex flow density (SVD) and deep vascular complex flow density (DVD) (P < .05), but no significant correlation with choroidal capillary density (P > .05); inner retinal thickness showed a weak positive correlation with SVD and DVD (P < .05), but no significant correlation with choroidal capillary density (P > .05). In pediatric patients with myopia, there is a positive correlation between the blood flow density of macular retina and retinal thickness, and the retinal thickness will become thinner with increasing myopia.

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Conflict of interest statement

The authors have no funding and conflicts of interest to disclose.

Figures

Figure 1.
Figure 1.
Thickness of outer retina showed a low degree of positive correlation with SVD and DVD. DVD = deep vascular complex flow density, SVD = superficial vascular complex flow density.
Figure 2.
Figure 2.
Thickness of inner retina showed a low degree of positive correlation with SVD and DVD. DVD = deep vascular complex flow density, SVD = superficial vascular complex flow density.
Figure 3.
Figure 3.
No correlation between thickness of outer retina and choroidal capillary density.
Figure 4.
Figure 4.
No correlation between thickness of inner retina and choroidal capillaries density.
See this image and copyright information in PMC

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