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Comment
. 2024 Jul 25;84(14):2591-2592.
doi: 10.1016/j.molcel.2024.06.012.

Splicing regulation of DNA repair via CCAR1

Yuxi Ai  1 , Omar Abdel-Wahab  2
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Splicing regulation of DNA repair via CCAR1

Yuxi Ai et al. Mol Cell. .
Free article

Abstract

In this issue of Molecular Cell, Harada et al.1 and Karasu et al.2 identify CCAR1 as a novel regulator of the Fanconi anemia/BRCA DNA repair pathway via modulating the splicing of the mRNA encoding FANCA.

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Conflict of interest statement

Declaration of interests O.A.-W. is a founder and scientific advisor of Codify Therapeutics, holds equity in this company, and receives research funding from this company. O.A.-W. has served as a consultant for Foundation Medicine, Inc.; Merck; Prelude Therapeutics; Amphista Therapeutics; MagnetBio; and Janssen and is on the scientific advisory board of Envisagenics, Inc.; Harmonic Discovery, Inc.; and Pfizer Boulder. O.A.-W. has received prior research funding from H3B Biomedicine, Nurix Therapeutics, Minovia Therapeutics, and LOXO Oncology unrelated to the current manuscript.

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