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Review
. 2024 Sep;25(5):765-778.
doi: 10.1007/s40257-024-00880-1. Epub 2024 Jul 26.

Hidradenitis Suppurativa: New Targets and Emerging Treatments

Julia L Gao  1   2 , Tracey S Otto  1   2 , Martina L Porter  1   2 , Alexa B Kimball  3   4
Affiliations
Review

Hidradenitis Suppurativa: New Targets and Emerging Treatments

Julia L Gao et al. Am J Clin Dermatol. 2024 Sep.

Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition that can be challenging to treat. Biologics and targeted small molecules have become an increasingly popular area of investigation for therapeutic development for moderate-to-severe HS, though only three biologics-adalimumab, secukinumab, and bimekizumab-have received US Food and Drug Administration (FDA) or European Medicines Evaluation Agency approval for treating HS. Promising agents under investigation are targeting interleukin 17A/F, JAK/STAT pathway, interleukin 36, interleukin 1, and more.

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References

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