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. 2024 Jul 11;14(7):691.
doi: 10.3390/brainsci14070691.

The Impact of Social Cognition Deficits on Quality of Life in Multiple Sclerosis: A Scoping Review

Giulia Marafioti  1 , Davide Cardile  1 , Laura Culicetto  1 , Angelo Quartarone  1 , Viviana Lo Buono  1
Affiliations

The Impact of Social Cognition Deficits on Quality of Life in Multiple Sclerosis: A Scoping Review

Giulia Marafioti et al. Brain Sci. .

Abstract

Background: Multiple Sclerosis (MS) is a chronic neurological disease that affects the Central Nervous System by causing demyelination. Social cognition (SC) deficits are common among individuals with MS and can significantly impact their quality of life (QoL) due to difficulties in interpreting social cues and establishing meaningful relationships.

Objective: This scoping review aimed to investigate SC in subjects with MS and its impact on QoL.

Methods: Systematic searches were performed in PubMed, Scopus, Embase, and Web of Science databases. After reading the full text of the selected studies and applying predefined inclusion criteria, four studies were included based on pertinence and relevance to the topic.

Results: The findings highlight significant associations between SC deficits, social support, fatigue, and QoL outcomes. Cognitive decline was identified as a predictive factor for SC impairment in the MS population, which affects daily activities and relationships, thereby reducing QoL. Moreover, emotional impairments such as depression and anxiety exacerbate these challenges. Enhancing social support networks may improve psychological well-being and disease management in MS.

Conclusions: Although evidence is limited, assessing SC is crucial in the care pathways for MS to develop tailored psychosocial interventions that address the cognitive, emotional, and social facets of the disease, thereby improving overall outcomes and QoL.

Keywords: multiple sclerosis; quality of life; social cognition.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
PRISMA diagram for the current review.
See this image and copyright information in PMC

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