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Review
. 2024 Jul 10;13(14):4019.
doi: 10.3390/jcm13144019.

The Predictive Value of Aortic Calcification on Computed Tomography for Major Cardiovascular Events

David-Dimitris Chlorogiannis  1 , Sumant Pargaonkar  2 , Anastasios Apostolos  3 , Nikolaos Vythoulkas-Biotis  4 , Damianos G Kokkinidis  5 , Sanjana Nagraj  6
Affiliations
Review

The Predictive Value of Aortic Calcification on Computed Tomography for Major Cardiovascular Events

David-Dimitris Chlorogiannis et al. J Clin Med. .

Abstract

As the prevalence of cardiovascular disease continues to increase, early identification of patients at high risk of major adverse cardiovascular events (MACE) using reliable diagnostic modalities is important. Transcatheter aortic valve implantation (TAVI) is a minimally invasive percutaneous procedure used to replace the aortic valve with a bioprosthetic one, often without the need for surgery. Extra coronary calcification in the ascending and/or descending thoracic aorta, aortic arch, and abdominal aorta has recently been identified as a method to quantify the extent of atherosclerotic cardiovascular disease. However, its definitive role in the prediction of MACE remains unclear. We performed a comprehensive review to summarize the current literature on the diagnostic and predictive value of thoracic and abdominal aortic calcification, as quantified in computed tomography, for the association, risk stratification, and prediction of MACE and after TAVI procedures. Despite increasing evidence, the predictive role of thoracic calcification still remains unproven, with a need for carefully tailored studies to confirm these findings.

Keywords: TAVI; aortic calcification; cardiovascular events; computed tomography; major cardiovascular events.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Ascending thoracic aorta calcification (ATAC) extending from above the level of the aortic annulus to the lower edge of the pulmonary artery. Descending thoracic aorta calcification (DTAC) from the lower edge of the pulmonary artery to the cardiac apex.
See this image and copyright information in PMC

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