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Multicenter Study
. 2024 Jun 24;60(7):1033.
doi: 10.3390/medicina60071033.

Stress and Quality of Life in Caregivers of Patients with Multiple Sclerosis

Anastasios Kantanis  1   2 , Maria Pelantaki  1 , Maria Lidia Fountaki  1 , Vasilios Konstantopoulos  1 , Themistoklis Paraskevas  1 , Evgenia Stavropoulou  1 , Eirini Tsiamaki  3 , Nikolaos Trimmis  1   2 , Panagiotis Plotas  1   2
Affiliations
Multicenter Study

Stress and Quality of Life in Caregivers of Patients with Multiple Sclerosis

Anastasios Kantanis et al. Medicina (Kaunas). .

Abstract

Background and Objectives: Multiple sclerosis is a chronic demyelinating disease of the central nervous system. Individuals with multiple sclerosis may require daily care and support from caregivers due to the disease's progressive and unpredictable nature. However, the role of caregiving is not without its challenges, and caregivers themselves often face significant repercussions in terms of their quality of life, mental health, and stress levels. Our study aims to investigate the level of stress caregivers experience in their everyday life and the way stress affects their quality of life. Materials and Methods: We conducted a multicenter, cross-sectional study from 11 November 2023 to 20 March 2024 in healthcare units in Western Greece. All 96 participants were adult caregivers of patients diagnosed with multiple sclerosis (MS). We assessed caregivers' quality of life and stress levels using the 36-item Short Form Health Survey and Kingston Caregiver Stress Scale, respectively. Non-parametric tests (Spearman's rho test, Kruskal-Wallis and Mann-Whitney tests) were used to identify possible correlations between the aforementioned scales and between stress levels and caregiver characteristics. Results: Caregivers reported high stress, with an average KCSS score of 36.82 ± 0.851. The mean SF-36 physical component summary score (PCS) was 59.59 ± 2.77, whereas the mental component summary score (MCS) was 45.69 ± 2.32. Stress levels in the KCSS were negatively correlated with both PCS and MCS of SF-36 and female gender, education level, monthly income, limits of mobility, and patient's level of dependence were associated with higher levels of stress. Conclusions: Stress was found to be negatively connected with caregivers' quality of life, affecting both physical and mental health. Female caregivers, caregivers with a primary education level and a low monthly income, and caregivers of patients with serious illnesses who rely primarily on daily help were the most affected.

Keywords: anxiety; caregivers; multiple sclerosis; quality of life.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
KCSS score and caregiver’s gender.
Figure 2
Figure 2
KCSS score and caregiver’s education levels.
Figure 3
Figure 3
KCSS score and caregiver’s monthly income.
Figure 4
Figure 4
KCSS and patient’s limits of mobility.
Figure 5
Figure 5
KCSS and patient’s level of dependence.
See this image and copyright information in PMC

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References

    1. Walton C., King R., Rechtman L., Kaye W., Leray E., Marrie R.A., Robertson N., La Rocca N., Uitdehaag B., Van Der Mei I., et al. Rising prevalence of multiple sclerosis worldwide: Insights from the Atlas of MS, third edition. [(accessed on 12 April 2024)];Mult. Scler. J. 2020 26:1816–1821. doi: 10.1177/1352458520970841. Available online: https://pubmed.ncbi.nlm.nih.gov/33174475/ - DOI - PMC - PubMed
    1. New Prevalence and Incidence Data Now Available in the Atlas of MS—MS International Federation. [(accessed on 25 May 2024)]. Available online: https://www.msif.org/news/2023/08/21/new-prevalence-and-incidence-data-n...
    1. Wallin M.T., Culpepper W.J., Nichols E., Bhutta Z.A., Gebrehiwot T.T., Hay S.I., Khalil I.A., Krohn K.J., Liang X., Naghavi M., et al. Global, regional, and national burden of multiple sclerosis 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016. [(accessed on 25 May 2024)];Lancet Neurol. 2019 18:269–285. doi: 10.1016/S1474-4422(18)30443-5. Available online: http://www.thelancet.com/article/S1474442218304435/fulltext. - DOI - PMC - PubMed
    1. Campbell J.D., Ghushchyan V., McQueen R.B., Cahoon-Metzger S., Livingston T., Vollmer T., Corboy J., Miravalle A., Schreiner T., Porter V., et al. Burden of multiple sclerosis on direct, indirect costs and quality of life: National US estimates. [(accessed on 12 April 2024)];Mult. Scler. Relat. Disord. 2014 3:227–236. doi: 10.1016/j.msard.2013.09.004. Available online: https://pubmed.ncbi.nlm.nih.gov/25878010/ - DOI - PubMed
    1. Santos M., Sousa C., Pereira M., Pereira M.G. Quality of life in patients with multiple sclerosis: A study with patients and caregivers. [(accessed on 13 February 2023)];Disabil. Health J. 2019 12:628–634. doi: 10.1016/j.dhjo.2019.03.007. Available online: https://pubmed.ncbi.nlm.nih.gov/31005483/ - DOI - PubMed

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