An executive summary on the Global conceptual definition of Sarcopenia

Ben Kirk^{1

2}, Peggy M Cawthon^{3

4}, Hidenori Arai⁵, José A Ávila-Funes^{6

7}, Rocco Barazzoni⁸, Shalender Bhasin⁹, Ellen F Binder¹⁰, Olivier Bruyère^{11

12}, Tommy Cederholm^{13

14}, Liang-Kung Chen^{15

16}, Cyrus Cooper^{17

18}, Gustavo Duque^{19

20}, Roger A Fielding²¹, Jack Guralnik²², Douglas P Kiel²³, Francesco Landi²⁴, Jean-Yves Reginster^{25

26}, Avan A Sayer²⁷, Marjolein Visser^{28

29}, Stephan von Haehling^{30

31}, Jean Woo³², Alfonso J Cruz-Jentoft³³; Global Leadership Initiative in Sarcopenia (GLIS) Group

Affiliations

¹ Department of Medicine, Western Health, Melbourne Medical School, University of Melbourne, St Albans, Melbourne, VIC, Australia.
² Australian Institute for Musculoskeletal Science (AIMSS), University of Melbourne and Western Health, St Albans, Melbourne, VIC, Australia.
³ California Pacific Medical Center, Research Institute, 550 16th Street, Second Floor, San Francisco, CA, 94143, USA.
⁴ Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.
⁵ National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
⁶ Department of Geriatrics, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, Mexico.
⁷ Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, UMR 1219, 33000, Bordeaux, France.
⁸ Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
⁹ Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
¹⁰ Division of General Medicine and Geriatrics, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
¹¹ WHO Collaborating Center for Public Health Aspects of Musculo-Skeletal Health and Ageing, Division of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium.
¹² Department of Sport and Rehabilitation Sciences, University of Liège, Liège, Belgium.
¹³ Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden.
¹⁴ Theme Inflammation and Ageing, Karolinska University Hospital, Stockholm, Sweden.
¹⁵ Center for Geriatrics and Gerontology, Taipei Veterans General Hospital, Taipei, Taiwan.
¹⁶ Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
¹⁷ MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.
¹⁸ Department of Epidemiology, University of Oxford, Oxford, OX, UK.
¹⁹ Bone, Muscle and Geroscience Group, Research Institute of the McGill University Health Centre, Montreal, QC, Canada.
²⁰ Dr. Joseph Kaufmann Chair in Geriatric Medicine, Department of Medicine, McGill University, Montreal, QC, Canada.
²¹ Nutrition Exercise, Physiology, and Sarcopenia Laboratory, Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center On Aging, Tufts University, Boston, MA, USA.
²² Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.
²³ Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Department of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
²⁴ Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00168, Rome, Italy.
²⁵ WHO Collaborating Center for Epidemiology of Musculoskeletal Health and Aging, Liège, Belgium.
²⁶ Chair for Biomarkers of Chronic Diseases, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.
²⁷ AGE Research Group, NIHR Newcastle Biomedical Research Centre, Newcastle Hospitals and Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
²⁸ Department of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
²⁹ The Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
³⁰ Department of Cardiology and Pneumology, University Medicine Göttingen (UMG), Göttingen, Germany.
³¹ German Centre for Cardiovascular Research (DZHK), Partner Site Göttingen, Göttingen, Germany.
³² Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.
³³ Servicio de Geriatría, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain. alfonsojose.cruz@salud.madrid.org.

PMID: 39066819
PMCID: PMC11283377
DOI: 10.1007/s40520-024-02798-4

An executive summary on the Global conceptual definition of Sarcopenia

Ben Kirk et al. Aging Clin Exp Res. 2024.

. 2024 Jul 27;36(1):153.

doi: 10.1007/s40520-024-02798-4.

Authors

Affiliations

¹ Department of Medicine, Western Health, Melbourne Medical School, University of Melbourne, St Albans, Melbourne, VIC, Australia.
² Australian Institute for Musculoskeletal Science (AIMSS), University of Melbourne and Western Health, St Albans, Melbourne, VIC, Australia.
³ California Pacific Medical Center, Research Institute, 550 16th Street, Second Floor, San Francisco, CA, 94143, USA.
⁴ Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.
⁵ National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
⁶ Department of Geriatrics, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, Mexico.
⁷ Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, UMR 1219, 33000, Bordeaux, France.
⁸ Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
⁹ Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
¹⁰ Division of General Medicine and Geriatrics, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
¹¹ WHO Collaborating Center for Public Health Aspects of Musculo-Skeletal Health and Ageing, Division of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium.
¹² Department of Sport and Rehabilitation Sciences, University of Liège, Liège, Belgium.
¹³ Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden.
¹⁴ Theme Inflammation and Ageing, Karolinska University Hospital, Stockholm, Sweden.
¹⁵ Center for Geriatrics and Gerontology, Taipei Veterans General Hospital, Taipei, Taiwan.
¹⁶ Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
¹⁷ MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.
¹⁸ Department of Epidemiology, University of Oxford, Oxford, OX, UK.
¹⁹ Bone, Muscle and Geroscience Group, Research Institute of the McGill University Health Centre, Montreal, QC, Canada.
²⁰ Dr. Joseph Kaufmann Chair in Geriatric Medicine, Department of Medicine, McGill University, Montreal, QC, Canada.
²¹ Nutrition Exercise, Physiology, and Sarcopenia Laboratory, Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center On Aging, Tufts University, Boston, MA, USA.
²² Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.
²³ Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Department of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
²⁴ Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00168, Rome, Italy.
²⁵ WHO Collaborating Center for Epidemiology of Musculoskeletal Health and Aging, Liège, Belgium.
²⁶ Chair for Biomarkers of Chronic Diseases, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.
²⁷ AGE Research Group, NIHR Newcastle Biomedical Research Centre, Newcastle Hospitals and Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
²⁸ Department of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
²⁹ The Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
³⁰ Department of Cardiology and Pneumology, University Medicine Göttingen (UMG), Göttingen, Germany.
³¹ German Centre for Cardiovascular Research (DZHK), Partner Site Göttingen, Göttingen, Germany.
³² Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.
³³ Servicio de Geriatría, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain. alfonsojose.cruz@salud.madrid.org.

PMID: 39066819
PMCID: PMC11283377
DOI: 10.1007/s40520-024-02798-4

No abstract available

Keywords: Muscle mass; Muscle strength; Sarcopenia.

PubMed Disclaimer

Conflict of interest statement

All authors declarations of conflicts of interests and declarations of sources of funding can be read here: https://www.eugms.org/fileadmin/images/news/2022/GLIS_Steering_Committee_Rev3.pdf

Figures

**Fig. 1**
The list of accepted and rejected statements from the Delphi study (n = 107 participants). Sourced from Kirk et al. [1]

**Fig. 2**
The global conceptual definition of Sarcopenia. Sourced from Kirk et al. [1]

See this image and copyright information in PMC

References

1. Kirk B, Cawthon PM, Arai H et al (2024) The conceptual definition of sarcopenia: Delphi consensus from the global leadership initiative in sarcopenia (GLIS). Age Ageing. 10.1093/ageing/afae052 10.1093/ageing/afae052 - DOI - PMC - PubMed
1. Cawthon PM, Visser M, Arai H et al (2022) Defining terms commonly used in sarcopenia research: a glossary proposed by the global leadership in sarcopenia (GLIS) steering committee. Eur Geriatr Med 13:1239–1244. 10.1007/S41999-022-00706-5 10.1007/S41999-022-00706-5 - DOI - PMC - PubMed

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An executive summary on the Global conceptual definition of Sarcopenia

Affiliations

An executive summary on the Global conceptual definition of Sarcopenia

Authors

Affiliations

Conflict of interest statement

Figures

References

MeSH terms

LinkOut - more resources

Full Text Sources