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. 2025 Apr 30;80(4):804-806.
doi: 10.1093/cid/ciae392.

Beyond the Timeline: 1-Year Mortality Trends in Early Versus Late Prosthetic Valve Endocarditis

Matthaios Papadimitriou-Olivgeris  1   2 , Bruno Ledergerber  3 , Berit Siedentop  3 , Pierre Monney  4 , Michelle Frank  5 , Georgios Tzimas  4 , Piergiorgio Tozzi  6 , Matthias Kirsch  6 , Jana Epprecht  3 , Mathias van Hemelrijck  7 , Omer Dzemali  7   8 , Benoit Guery  1 , Barbara Hasse  3
Affiliations

Beyond the Timeline: 1-Year Mortality Trends in Early Versus Late Prosthetic Valve Endocarditis

Matthaios Papadimitriou-Olivgeris et al. Clin Infect Dis. .

Abstract

Among 302 episodes of prosthetic valve endocarditis (PVE), 1-year mortality was 31%. There was no evidence indicating that early-onset PVE within 6 months from valve surgery led to a worse outcome compared to late-onset PVE (21% vs 32%, P = .126), despite similar redo valve surgeries across both categories.

Keywords: embolic events; heart failure; infective endocarditis; periannular complications; prosthetic valve endocarditis; transcatheter aortic valve implantation (TAVI); valve surgery.

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Conflict of interest statement

Potential conflicts of interest . The authors: No reported conflicts of interest. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest.

Figures

Graphical Abstract
Graphical Abstract
This graphical abstract is also available at Tidbit: https://tidbitapp.io/tidbits/beyond-the-timeline-one-year-mortality-trends-in-early-vs-late-prosthetic-valve-endocarditis
Figure 1.
Figure 1.
Kaplan-Meier analysis comparing mortality rates between early (≤6 months postsurgery [21%]) and late (>6 months postsurgery [32%]) prosthetic valve endocarditis (PVE) (log-rank test P = .134).
See this image and copyright information in PMC

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