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. 2024 Sep-Oct:51:100689.
doi: 10.1016/j.ijmmb.2024.100689. Epub 2024 Aug 1.

Leptospirosis in central India: A retrospective study to explore burden of tropical illness

H V Manjunathachar  1 , Pradip V Barde  2 , Vivek Chouksey  3 , Prakash Tiwari  4 , Basavaraj Mathapati  5 , Suyesh Shrivastava  6 , Tapas Chakma  7
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Leptospirosis in central India: A retrospective study to explore burden of tropical illness

H V Manjunathachar et al. Indian J Med Microbiol. 2024 Sep-Oct.

Abstract

Leptospirosis, an underdiagnosed zoonotic disease in India, was studied retrospectively in Madhya Pradesh, Central India. Between 2018 and 2019, 2617 samples from patients with hepatitis-related symptoms were collected. Of these, 518 tested negative for hepatitis and other tropical viral diseases under the VRDL project were analyzed for leptospira IgM using ELISA. 68 (13.12%) were positive for leptospirosis. Common symptoms included fever (97.45%) and jaundice (42.27%), with renal involvement in 30.88% of cases. Higher incidence was observed in the 31-60 age group, especially during monsoon and post-monsoon seasons. The study highlights the need for increased clinician awareness and inclusion of leptospirosis in screening panels to differentiate tropical illnesses in India.

Keywords: Central India; Leptospirosis; Zoonoses.

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Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the research work reported here.

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