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Review
. 2025;32(20):3945-3959.
doi: 10.2174/0109298673295600240725060349.

Antiprotozoal, Anthelmintic and Antivectorial Activities of Titanium Dioxide Nanoparticles

Thainá Silva Bologna  1 , Isabella de Oliveira Ferrato de Sousa  1 , Jose Rodrigues do Carmo Neto  2 , Thais Amanda de Lima Nunes  1 , Beatriz Sodre Matos  1 , Priscilla Elias Ferreira da Silva  1 , Rhanoica Oliveira Guerra  3 , Pablo Igor Ribeiro Franco  2 , Juliana Reis Machado  2   4 , Anielle Christine Almeida Silva  5 , Marcos Vinicius da Silva  1
Affiliations
Review

Antiprotozoal, Anthelmintic and Antivectorial Activities of Titanium Dioxide Nanoparticles

Thainá Silva Bologna et al. Curr Med Chem. 2025.

Abstract

Nanotechnology has been established as a promising alternative for treating a myriad of disease-causing microorganisms that pose threats to human health. The utilization of nanoparticles (NPs) emerges as a strategy to enhance the therapeutic arsenal against these diseases, especially given the tendency of many pathogens to develop resistance to conventional medications. Notably, titanium dioxide nanoparticles (TiO2NPs) have garnered attention for their multifaceted biomedical applications, encompassing antibacterial, antifungal, antiviral, anticancer, antioxidant, and drug delivery properties. This review focuses on the cutting-edge potential of TiO2NPs against helminths, protozoa, and vectors, underscoring their pivotal role in combating these health-threatening agents.

Keywords: Nanocomposite; anthelmintic; antiprotozoal; biosensor; nanoparticles; reptiles.; titanium dioxide.

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