Anaplastic thyroid cancer: Unveiling advances in diagnosis and management
- PMID: 39071466
- PMCID: PMC11271728
- DOI: 10.5306/wjco.v15.i7.786
Anaplastic thyroid cancer: Unveiling advances in diagnosis and management
Abstract
The review article by Pavlidis et al published in World J Clin Oncol provides a meticulous analysis of the intricacies surrounding anaplastic carcinoma of the thyroid. Thyroid carcinoma encompasses a spectrum of diseases, each characterized by distinct behaviors and outcomes. Diagnostic approaches encompass a diverse array of tools. Surgery remains the pivotal treatment for anaplastic thyroid carcinoma. Radiotherapy and chemotherapy offer the best overall survival in aggressive disease. Combinations of immunotherapy with targeted therapies, such as dabrafenib-trametinib, demonstrate potential for enhanced effectiveness and improved survival outcomes. Multifaceted approach fuelled by precision medicine and interdisciplinary collaboration is imperative in charting a course toward improved outcomes in this formidable malignancy.
Keywords: Anaplastic thyroid cancer; Chemotherapy; Immunotherapy; Radiotherapy; Surgery; Targeted therapy.
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Conflict of interest statement
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
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