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Review
. 2024 Sep;101(3):223-233.
doi: 10.1111/cen.15110. Epub 2024 Jul 29.

Paediatric thyroid disease

Timothy Cheetham  1 , Claire Wood  1
Affiliations
Review

Paediatric thyroid disease

Timothy Cheetham et al. Clin Endocrinol (Oxf). 2024 Sep.

Abstract

The spectrum of thyroid disorders presenting to paediatricians is different to that seen by adult physicians. Referrals reflect cases detected by the neonatal screening programme for congenital hypothyroidism and many of the inherited defects of thyroid hormone generation or action will be manifest in early life. Autoimmune thyroid disease can be particularly challenging to manage in the young and the potential impact of thyroid status on neurodevelopment and schooling are key considerations throughout childhood and adolescence.

Keywords: Graves; central hypothyroidism; congenital hypothyroidism; thyroid disease.

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References

REFERENCES

    1. Kummer S, Hermsen D, Distelmaier F. Biotin treatment mimicking Graves' disease. N Engl J Med. 2016;375(7):704‐706.
    1. Khoo S, Lyons G, McGowan A, et al. Familial dysalbuminaemic hyperthyroxinaemia interferes with current free thyroid hormone immunoassay methods. Eur J Endocrinol. 2020;182(6):533‐538.
    1. van Trotsenburg P, Stoupa A, Léger J, et al. Congenital hypothyroidism: a 2020‐2021 consensus guidelines update‐An ENDO‐European reference network initiative endorsed by the european society for pediatric endocrinology and the European society for endocrinology. Thyroid. 2021;31(3):387‐419.
    1. Pollitt RJ. Evidence or enthusiasm? Why yields from UK newborn screening programmes for congenital hypothyroidism are increasing. Arch Dis Child. 2016;101(2):120‐123.
    1. Larrivée‐Vanier S, Jean‐Louis M, Magne F, et al. Whole‐Exome sequencing in congenital hypothyroidism due to thyroid dysgenesis. Thyroid. 2022;32(5):486‐495.

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