Complex interaction of infusion volumes and confounding factors with lactate clearance in septic shock. Author's reply

Christian Ahlstedt^{1

2}, Praleene Sivapalan^{3

4

5}, Olav Rooyackers^{6

7}, Anders Perner^{3

4

5}, Jonathan Grip^{6

7}

Affiliations

¹ Department of Perioperative Medicine and Intensive Care (PMI), Karolinska University Hospital Huddinge, Stockholm, Sweden. Christian.Ahlstedt@ki.se.
² Division of Anaesthesia and Intensive Care, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institute, Stockholm, Sweden. Christian.Ahlstedt@ki.se.
³ Department of Intensive Care, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
⁴ Collaboration for Research in Intensive Care (CRIC), Copenhagen, Denmark.
⁵ Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
⁶ Department of Perioperative Medicine and Intensive Care (PMI), Karolinska University Hospital Huddinge, Stockholm, Sweden.
⁷ Division of Anaesthesia and Intensive Care, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institute, Stockholm, Sweden.

Christian Ahlstedt et al. Intensive Care Med. 2024 Sep.

. 2024 Sep;50(9):1547-1548.

doi: 10.1007/s00134-024-07563-9. Epub 2024 Jul 29.

Christian Ahlstedt^{1

2}, Praleene Sivapalan^{3

4

5}, Olav Rooyackers^{6

7}, Anders Perner^{3

4

5}, Jonathan Grip^{6

7}

¹ Department of Perioperative Medicine and Intensive Care (PMI), Karolinska University Hospital Huddinge, Stockholm, Sweden. Christian.Ahlstedt@ki.se.
² Division of Anaesthesia and Intensive Care, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institute, Stockholm, Sweden. Christian.Ahlstedt@ki.se.
³ Department of Intensive Care, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
⁴ Collaboration for Research in Intensive Care (CRIC), Copenhagen, Denmark.
⁵ Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
⁶ Department of Perioperative Medicine and Intensive Care (PMI), Karolinska University Hospital Huddinge, Stockholm, Sweden.
⁷ Division of Anaesthesia and Intensive Care, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institute, Stockholm, Sweden.

No abstract available

References

1. Ishii J, Ohshimo S, Nishikimi M, Kyo M, Shime N (2024) Complex interaction of infusion volumes and confounding factors with lactate clearance in septic shock. Intensive Care Med. https://doi.org/10.1007/s00134-024-07530-4
1. Ahlstedt C, Sivapalan P, Kriz M, Jacobson G, Sylvest Meyhoff T, Skov Kaas-Hansen B, Holm M, Hollenberg J, Nalos M, Rooijackers O, Hylander Møller M, Cronhjort M, Perner A, Grip J (2024) Effects of restrictive fluid therapy on the time to resolution of hyperlactatemia in ICU patients with septic shock. A secondary post hoc analysis of the CLASSIC randomized trial. Intensive Care Med 50(5):678–686. https://doi.org/10.1007/s00134-024-07385-9
1. Meyhoff TS, Hjortrup PB, Wetterslev J, Sivapalan P, Laake JH, Cronhjort M et al (2022) Restriction of intravenous fluid in ICU patients with septic shock. N Engl J Med 386(26):2459–2470 - DOI - PubMed
1. Shapiro NI, Douglas IS, Brower RG, Brown SM, Exline MC, Ginde AA et al (2023) Early restrictive or liberal fluid management for sepsis-induced hypotension. N Engl J Med 388(6):499–510 - DOI - PubMed - PMC