Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2024 Aug 6;121(32):e2412255121.
doi: 10.1073/pnas.2412255121. Epub 2024 Jul 29.

Central role of brain regulatory T cells in the inflammatory cascade in Alzheimer's disease

Affiliations
Comment

Central role of brain regulatory T cells in the inflammatory cascade in Alzheimer's disease

Germán Plascencia-Villa et al. Proc Natl Acad Sci U S A. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Competing interests statement:The authors declare no competing interest.

Figures

Fig. 1.
Fig. 1.
Brain regulatory T cells in AD-like neurodegeneration. Illustration of the roles of aged CD8 T cells in the initial steps of neurodegeneration.

Comment on

  • Antigen-specific age-related memory CD8 T cells induce and track Alzheimer's-like neurodegeneration.
    Panwar A, Rentsendorj A, Jhun M, Cohen RM, Cordner R, Gull N, Pechnick RN, Duvall G, Mardiros A, Golchian D, Schubloom H, Jin LW, Van Dam D, Vermeiren Y, De Reu H, De Deyn PP, Raskatov JA, Black KL, Irvin DK, Williams BA, Wheeler CJ. Panwar A, et al. Proc Natl Acad Sci U S A. 2024 Jul 16;121(29):e2401420121. doi: 10.1073/pnas.2401420121. Epub 2024 Jul 12. Proc Natl Acad Sci U S A. 2024. PMID: 38995966 Free PMC article.

References

    1. Alzheimer’s Association, 2024 Alzheimer’s disease facts and figures. Alzheimer’s Dement. 20, 3708–3821 (2024). - PMC - PubMed
    1. Knopman D. S., et al. , Alzheimer disease. Nat. Rev. Dis. Primers 7, 33 (2021). - PMC - PubMed
    1. Zhang Q., et al. , Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture. Nat. Commun. 11, 4799 (2020). - PMC - PubMed
    1. Selkoe D. J., Hardy J., The amyloid hypothesis of Alzheimer’s disease at 25 years. EMBO Mol. Med. 8, 595–608 (2016). - PMC - PubMed
    1. Liston A., Pasciuto E., Fitzgerald D. C., Yshii L., Brain regulatory T cells. Nat. Rev. Immunol. 24, 326–337 (2024). - PubMed

LinkOut - more resources