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. 2024 Nov:274:114216.
doi: 10.1016/j.jpeds.2024.114216. Epub 2024 Jul 27.

Discordant Perception of Disease Activity Between Providers and Adolescents with Systemic Lupus Erythematosus: A Cohort Study

Zanab Mian  1 , Terrence Calistro  2 , Kimberly Rapoza  2 , Shari Salzhauer Berkowitz  3 , Tamar B Rubinstein  4 , Heather M Walters  1 , B Anne Eberhard  1 , Kathleen Kenney-Riley  5 , Joyce S Hui-Yuen  6
Affiliations

Discordant Perception of Disease Activity Between Providers and Adolescents with Systemic Lupus Erythematosus: A Cohort Study

Zanab Mian et al. J Pediatr. 2024 Nov.

Abstract

Discordance in perception of disease activity between adolescent patients with lupus and their providers may influence disease outcomes. We found that patients endorsed higher perceptions of disease activity than providers. Discordance was present at all levels of disease activity, particularly in patients with high activity, nephritis, and/or taking corticosteroids or mycophenolate mofetil.

Keywords: Pediatric rheumatology; discordance; outcome measures; systemic lupus erythematosus.

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Conflict of interest statement

Declaration of Competing Interest K.K.R., K.R., and S.B. are the recipients of grant funding (#2019-10021) from the National Institute on Disability, Independent Living and Rehabilitation Research (NIDILRR). T.B.R. is supported by the Childhood Arthritis and Rheumatology Research Alliance/Arthritis Foundation Career Development Award and the National Institute of Arthritis and Musculoskeletal Skin Diseases (NIAMS) (K23AR080803). The authors declare no conflicts of interest.

Figures

Figure.
Figure.
A, Provider GA stratified by SLEDAI scores. B, Patient GA stratified by SLEDAI scores. C, Absolute discordance in perception of disease activity between adolescents with lupus and their providers, stratified by SLEDAI scores.
See this image and copyright information in PMC

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